The reproducibility of endometrial volume acquisition and measurement with the VOCAL-imaging program

N Raine-Fenning, N. J. Raine‐Fenning, B Campbell, Bruce Campbell, Jacqueline Collier, J Collier, M. Brincat, I. R. Johnson, I Johnson
Ultrasound in Obstetrics & Gynecology · 2002 · vol. 19(1) , pp. 69–75 · doi:10.1046/j.0960-7692.2001.00608.x · PMID:11851972 · W2074058004
Case report OA: bronze CC0 ⤵ 9 in-corpus citations
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study found that endometrial volume measurements using the VOCAL-imaging program were reproducible, with rotational methods employing less than 30-degree steps showing significantly smaller variance and greater mean volumes.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVES: To determine the intraobserver reproducibility of volume acquisition and repeatability of endometrial volume measurements using the VOCAL-imaging program (Virtual Organ Computer-aided AnaLysis). METHODS: Ten three-dimensional (3D) ultrasound datasets of the same endometrium were obtained from one patient during one scan session. For every 3D dataset, the endometrial volume was calculated by four different measurement techniques; three rotational methods and one conventional method. A single observer acquired each dataset and conducted all measurements. For the rotational technique, the manual mode was used to trace the myometrial-endometrial border through three different predefined rotations of 30 degrees, 15 degrees and 9 degrees . Endometrial volume was also measured in a conventional manner by scrolling through one of the multiplanar images and outlining the contour in another. Ten consecutive measurements were taken for each of the four measurement techniques so that 40 endometrial volume readings were obtained for each of the 10 3D-ultrasound datasets. RESULTS: Endometrial volume measurements were more reproducible with the rotational technique. Rotational methods employing a rotation step of less than 30 degrees were associated with coefficients of variation below 1% and intraclass correlation coefficients above 0.94. Within each of the 10 different scans, the homogeneity of the variance of measurements was significantly different according to the method of measurement (P = 0.022 to < 0.001). Post-hoc tests revealed that both the conventional and 30 degrees rotational methods resulted in a significantly smaller mean endometrial volume than both the 15 degrees and the 9 degrees rotational methods. CONCLUSIONS: Endometrial volume acquisition is reproducible and endometrial volume measurements are repeatable but they depend upon the technique of volume calculation in so much as rotational methods employing a rotation step of less than 30 degrees are associated with a significantly smaller variance in measurements and a significantly greater mean endometrial volume.

My notes (saved in your browser only)

MeSH descriptors

Endometrium Image Processing, Computer-Assisted Imaging, Three-Dimensional User-Computer Interface Adult Endometrium Female Humans Reproducibility of Results Ultrasonography Ultrasonography

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (32)

Cited by (9)

Source provenance

openalex
last seen: 2026-05-11T05:50:48.314143+00:00
pubmed
last seen: 2026-10-08T21:00:24.492322+00:00
License: CC0 · commercial use OK