Adenomyosis and Abnormal Uterine Bleeding
Adenomyosis, classified into intrinsic, extrinsic, and intermediate types, presents challenges in diagnosing and treating abnormal uterine bleeding, with MRI guiding classification and treatment options for refractory cases.
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This paper/chapter describes adenomyosis as a cause of abnormal uterine bleeding, emphasizing that its pathogenesis and clinical manifestations vary and can be grouped into intrinsic, extrinsic, and intermediate types with different bleeding and pain patterns. It outlines that heavy menstrual flow and irregular bleeding can persist even during medical treatments such as LNG-IUS, GnRHa injections, or dienogest, and notes that intrinsic forms may show a clearer relationship to abnormal angiogenesis or other factors. The chapter states that MRI can support detailed classification of adenomyosis in cases with refractory bleeding and help delineate treatment options, but it does not provide original data or formal evidence synthesis within the text. Relevance to endometriosis: adenomyosis is discussed as a distinct cause of abnormal uterine bleeding with imaging and medical-therapy considerations, though the excerpt does not explicitly position it alongside endometriosis in the same way.
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References (25)
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- Combination of microwave endometrial ablation and postoperative dienogest administration is effective for treating symptomatic adenomyosis via openalex
- Current status of high-intensity focused ultrasound for the management of uterine adenomyosis via openalex
- Diffuse adenomyosis: comparison of endovaginal US and MR imaging with histopathologic correlation. via openalex
- Evaluation of NovaSure® global endometrial ablation in symptomatic adenomyosis: A longitudinal study with a 36 month follow-up via openalex
- Evaluation of the efficacy and safety of dienogest in the treatment of painful symptoms in patients with adenomyosis: a randomized, double-blind, multicenter, placebo-controlled study via openalex
- Four subtypes of adenomyosis assessed by magnetic resonance imaging and their specification via openalex
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- Long‐term dienogest administration in patients with symptomatic adenomyosis via openalex
- MRI for adenomyosis: a pictorial review via openalex
- Pharmacological Treatment for Symptomatic Adenomyosis: A Systematic Review via openalex
- Prevalence of abnormal uterine bleeding according to new International Federation of Gynecology and Obstetrics classification in Chinese women of reproductive age via openalex
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