Age at Menarche and Oxidative Stress Markers in Women with Endometriosis

Areti Augoulea, A. Kindis, Evaggelia Karopoulou, Nikolaos Tsoltos, Georgios Kaparos, Efstratios Tsakonas, K. Panoulis
In: SN Comprehensive Clinical Medicine · 2020 · vol. 2(1) , pp. 69–74 · doi:10.1007/s42399-019-00214-x · W2998171178
article OA: closed CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study found that women with endometriosis had an earlier age at menarche but no difference in serum levels of six oxidative stress markers compared to controls.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This laparoscopic case-control study evaluated six serum oxidative stress-related markers (ADMA, MCP1, MMP2, MMP9, RANTES, and VEGF-A) in 46 women undergoing laparoscopy, comparing 31 women with visually and histopathologically confirmed endometriosis to 15 without. No significant differences were detected between groups for any of the measured markers, and disease stage was not associated with marker levels. Women with endometriosis reported earlier age at menarche than controls (11.7 vs 12.6 years, p = 0.04). The paper’s caveat is that oxidative stress marker differences were not observed in this relatively small sample. This paper is centrally about endometriosis — it tests whether serum oxidative stress markers differ in women with endometriosis and reports an associated difference in age at menarche.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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