Danazol treatment of advanced breast cancer.

R. Charles Coombes, David P. Dearnaley, Janice Humphreys, Gazet Jc, Ford Ht, Nash Ag, Κ. Mashiter, Powles Tj
In: Cancer treatment reports · 1981 · vol. 64(10-11) , pp. 1073–6 · PMID:7459893 · W2411335891
article OA: closed CC0 ⤵ 8 in-corpus citations
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Abstract

Danazol, an effective agent in the treatment of benign breast disease, has been administrated to 41 patients with advanced breast cancer. These patients were treated with danazol for periods ranging from 1 to 40 weeks and responses were seen in seven of 41 (17%) patients. No responses were seen in the four premenopausal patients treated. Side effects were seen in nine of 41 (22%) patients, but in most patients these stopped when the dose of danazol was reduced. This preliminary study indicates that danazol may be an effective form of hormone treatment in patients with advanced breast cancer.

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