Characterisation of Microscopic Changes in Macroscopically Unaffected Peritoneum in Women with and without Endometriosis

Mira Luhmann, Vito Chiàntera, Jalid Sehouli, Sylvia Mechsner, M Laschke, M Menger, O Df, T Roskams, K Van Den Eynde, A Vanhie, D Peterse, M Barcena De Arellano, J Gericke, U Reichelt, A Okuducu, A Ebert, M Fukunaga, P Imesch, D Fink, T Rizner, S Kavoussi, C Lim, B Skinner, D Lebovic, S As-Sanie, R Burney, L Giudice, S Wanyonyi, E Sequeira, S Mukono, M Society For Reproductive, L Kao, A Levy, J Shaw, L Sobin, M Meyers, E Hopton, D Redwine, A Murphy, W Green, Bobbie, Dela Cruz, Z Rock, J, L Yocom, M Nisolle, B Paindaveine, A Bourdon, M Berlire, F Casanas-Roux, F Nezhat, C Allan, C Nezhat, D Martin, J Balasch, M Creus, F Fbregues, F Carmona, J Ordi, K Khan, V Chiantera, M Dessole, M Petrillo, A Lucidi, S Frangini, S Vlek, L Zhu, M Lier, M Ankersmit, J Ket, J Dekker, A Bricou, R Batt, C Chapron, P Koninckx, S Kennedy, D Barlow, I Sasson, H Taylor, R Gazvani, A Templeton, C Scheerer, P Bauer, J Sehouli, A Kaufmann, S Lindsay, D Luciano, A Luciano, K Schweppe, S Liu, X Xin, T Hua, R Shi, S Chi, M Luhmann, S Mechsner
In: Archives of Women Health and Care · 2021 · vol. 4(1) · doi:10.31038/awhc.2021413 · W4205781402
article OA: gold CC0 ⤵ 1 in-corpus citation
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Abstract

It is defined by the presence of endometriosis in macroscopically normal-looking tissue. Even though there have been further studies, the meaning of OME is still unclear. Firstly, it could have an important status in the pathogenesis of endometriosis. Secondly, it could also be a physiological phenomenon with no disease value. To find out more about the clinical relevance of OME we histologically examined tissue specimens derived from visually normal peritoneum of the paracolic gutters of women with and without EM to detect the possible occurrence of OME. Due to the fact, that endometriotic lesions are associated with the local inflammatory response we also investigated the occurrence of IC and angiogenesis in this tissue.

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endometriosis

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