MODERN ASPECTS OF ENDOMETRIOSIS TREATMENT. USE OF DIENOGEST

This paper is a narrative overview of modern approaches to treating endometriosis, with particular emphasis on dienogest, drawing on published pharmacodynamic, cellular, and clinical studies. It highlights evidence that dienogest can modulate endometriosis-related biology (including effects on aromatase, prostaglandin production, angiogenesis, apoptosis, progesterone receptor isoforms, inflammation-related pathways, and autophagy) and summarizes clinical observations and comparative work on pain and recurrence outcomes after surgical management, while noting that the included evidence spans diverse study designs. A key limitation is that the article functions as an overview rather than presenting new original analyses, and it relies on the heterogeneity of referenced studies and outcomes. This paper is centrally about endometriosis — it focuses specifically on modern treatment strategies and the use of dienogest in endometriosis.

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