Progesterone increases serum CA-125 in endometriosis

Hiroshi Ozasa, H Ozasa, Ozasa H, Noda Y, Yoichi Noda, Y Noda, Takahide Mori, T Mori, Mori T
Fertility and sterility · 1987 · vol. 47(4) , pp. 699–701 · doi:10.1016/s0015-0282(16)59125-0 · PMID:3471532 · W60300835
Non-randomised trial OA: closed CC0 ⤵ 6 in-corpus citations
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This study investigated the effect of progesterone on serum CA-125 levels in women with endometriosis, finding that progesterone administration led to an increase in CA-125.

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Abstract

Serum level of CA-125 was monitored up to 48 hours after injection of 125 mg P-in-oil into patients with or without endometriosis in the follicular phase of their menstrual cycle. Circulating CA-125 levels remained unchanged at around 5 U/ml during the observation period in patients without endometriosis; however, a significant elevation was observed at 30 hours after injection in those patients with endometriosis (from 19.6 U/ml before injection to 30.0 U/ml at 30 hours after injection, P less than 0.05).

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Condition tags

endometriosis

MeSH descriptors

Antigens, Neoplasm Endometriosis Progesterone Uterine Neoplasms 17 alpha-Hydroxyprogesterone Caproate 17 alpha-Hydroxyprogesterone Caproate Adult Adult Antigens, Neoplasm Antigens, Neoplasm Antigens, Tumor-Associated, Carbohydrate Antigens, Tumor-Associated, Carbohydrate Endometriosis Endometriosis Endometriosis Enzyme-Linked Immunosorbent Assay Enzyme-Linked Immunosorbent Assay Estradiol Estradiol Estradiol

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (7)

Cited by (6)

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