Progesterone increases serum CA-125 in endometriosis

Hiroshi Ozasa, H Ozasa, Ozasa H, Noda Y, Yoichi Noda, Y Noda, Takahide Mori, T Mori, Mori T
Fertility and sterility · 1987 · vol. 47(4) , pp. 699–701 · doi:10.1016/s0015-0282(16)59125-0 · PMID:3471532 · W60300835
article OA: closed CC0 ⤵ 6 in-corpus citations
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This study investigated the effect of progesterone on serum CA-125 levels in women with endometriosis, finding that progesterone administration led to an increase in CA-125.

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Abstract

Serum level of CA-125 was monitored up to 48 hours after injection of 125 mg P-in-oil into patients with or without endometriosis in the follicular phase of their menstrual cycle. Circulating CA-125 levels remained unchanged at around 5 U/ml during the observation period in patients without endometriosis; however, a significant elevation was observed at 30 hours after injection in those patients with endometriosis (from 19.6 U/ml before injection to 30.0 U/ml at 30 hours after injection, P less than 0.05).

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Condition tags

endometriosis

MeSH descriptors

Antigens, Neoplasm Endometriosis Progesterone Uterine Neoplasms 17 alpha-Hydroxyprogesterone Caproate Adult Antigens, Neoplasm Antigens, Tumor-Associated, Carbohydrate Endometriosis Endometriosis Enzyme-Linked Immunosorbent Assay Estradiol Estradiol Female Follicular Phase Humans Hydroxyprogesterones Hydroxyprogesterones Hydroxyprogesterones Injections, Intramuscular

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (7)

Cited by (6)

Source provenance

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License: CC0 · commercial use OK