Endometriosis 1990

R L Barbieri, Robert L. Barbieri
Drugs · 1990 · vol. 39(4) , pp. 502–510 · doi:10.2165/00003495-199039040-00003 · PMID:2190793 · W2043944286
review OA: closed CC0 ⤵ 29 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

Endometriosis affects women of reproductive age with pelvic pain, infertility, or masses, and current hormonal treatments like danazol and GnRH agonists have varying side effect profiles.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 ⓘ

This article reviews endometriosis as a common reproductive-age gynecologic disease and summarizes typical clinical presentations (pelvic pain, infertility, or endometriomas) and current treatment approaches, with an emphasis on hormonal regimens following surgery for endometriomas. It reports that randomized controlled trials indicate danazol and GnRH agonists are similarly effective for treating endometriosis, while the main tradeoff is differing side-effect profiles (androgenic effects with danazol versus hypoestrogenism-related effects with GnRH agonists). The paper also states there is no evidence that hormonal therapy improves fecundability in women with endometriosis-associated infertility, though hormonal agents can successfully treat endometriosis-related pelvic pain in most patients, and concludes that an ideal regimen has not yet been developed. This paper is centrally about endometriosis — it is a 1990 review summarizing treatment options, trial outcomes, and side effects for endometriosis management.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Female Humans

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References (21)

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License: CC0 · commercial use OK