Chronic inflammation in endometriosis and endometriosis-associated ovarian cancer: New roles for the “old” complement pathway
article
OA: gold
CC0
⤵ 18 in-corpus citations
AI-generated summary
This study analyzed immune gene expression in endometriosis and endometriosis-associated ovarian cancer to explore new mechanistic roles for the complement pathway in immune escape during early carcinogenesis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
Abstract
Immune escape is consequential for cancer development. Identifying abnormalities of the immune microenvironment during early carcinogenesis can provide insight into disease pathogenesis and unravel new preventive or therapeutic targets. We recently conducted a comprehensive immune gene expression analysis in endometriosis and endometriosis-associated ovarian cancer and explored new mechanistic roles for the complement pathway.
My notes (saved in your browser only)
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (10)
- A conditional mouse model for human MUC1-positive endometriosis shows the presence of anti-MUC1 antibodies and Foxp3+ regulatory T cells via openalex
- <b>Ovarian atypical endometriosis: its close association with malignant epithelial tumours</b> via openalex
- Complement Pathway Is Frequently Altered in Endometriosis and Endometriosis-Associated Ovarian Cancer via openalex
- Expression of Natural Cytotoxicity Receptors on Peritoneal Fluid Natural Killer Cell and Cytokine Production by Peritoneal Fluid Natural Killer Cell in Women with Endometriosis via openalex
- Plasma MicroRNAs as Novel Biomarkers for Endometriosis and Endometriosis-Associated Ovarian Cancer via openalex
- W2167856596 via openalex
- W2029566727 via openalex
- W2065079849 via openalex
- W2125681453 via openalex
- W1967862947 via openalex
Cited by (18)
- The complement system and endometriosis: what's new? 2023
- Evaluation of Immune Infiltrates in Ovarian Endometriosis and Endometriosis-Associated Ovarian Cancer: Relationship with Histological and Clinical Features 2023
- Immunological Basis of the Endometriosis: The Complement System as a Potential Therapeutic Target 2021
- Peritoneal Modulators of Endometriosis-Associated Ovarian Cancer 2021
- Gene expression analysis signifies the association of inflammatory proteins with the development of endometriosis 2020
- The recent progress and therapy in endometriosis-associated ovarian cancer 2020
- The Many Faces of Endometriosis-Related Neoplasms in the Same Patient: A Brief Report 2020
- Vitamin D deficiency as a risk factor for endometriosis in Iranian women 2020
- Genetic variants in the nucleotide excision repair genes are associated with the risk of developing endometriosis 2019
- Hormones and Inflammation: An Update on Endometriosis 2019
- Machine Learning Classifiers for Endometriosis Using Transcriptomics and Methylomics Data 2019
- Endometriosis-associated ovarian cancer: What have we learned so far? 2019
- Altered Immunity in Endometriosis: What Came First? 2018
- Endometriosis and endometriosis-associated cancers: new insights into the molecular mechanisms of ovarian cancer development 2018
- The link between immunity, autoimmunity and endometriosis: a literature update 2018
- Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma 2017
- Endometriosis and Ovarian Cancer: From Molecular Evidences to Clinical Implications 2015
- Endometriosis and Ovarian Cancer: From Molecular Evidences to Clinical Implications 2015
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:17:46.044120+00:00
License: CC0
· commercial use OK