How can mitochondrial DNA deletions act as a biomarker for the detection of endometriosis within the clinic?

Jennifer Creed, Creed JM, Jennifer M Creed, Andrea Maggrah, Maggrah A, Usher R, Robert Usher, Elise Desa, Desa E, Andrew Harbottle, Harbottle A
Biomarkers in medicine · 2019 · vol. 14(1) , pp. 5–8 · doi:10.2217/bmm-2019-0435 · PMID:31686548 · W2986299521
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Large-scale deletions within the mitochondrial genome represent a promising biomarker for endometriosis detection, potentially overcoming limitations of existing diagnostic methods.

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Abstract

these features of the mitochondrial genome, its mutated subtypes and especially large-scale deletions, potentially resolve limitations of endometriosis biomarkers of different origins and offer the promise of successful translation to clinical application.

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Condition tags

endometriosis

MeSH descriptors

Biomarkers DNA, Mitochondrial Endometriosis Mutation Mutation Sequence Deletion Sequence Deletion Biomarkers Biomarkers Disease Progression Disease Progression DNA, Mitochondrial DNA, Mitochondrial DNA, Mitochondrial Endometriosis Endometriosis Endometriosis Female Female Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (17)

Cited by (4)

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