Clear cell ovarian adenocarcinoma

Yoonessi M, Mahmood Yoonessi, M Yoonessi, David Weldon Facog, D Weldon, Weldon D, Satchidand SK, Sateesh K. Satchidand, S K Satchidand, Kent Crickard, K Crickard, Crickard K
Journal of surgical oncology · 1984 · vol. 27(4) , pp. 289–297 · doi:10.1002/jso.2930270420 · PMID:6503304 · W2014380284
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This retrospective analysis of 22 clear cell ovarian carcinoma cases found a link with endometriosis and endometrial carcinoma, observed hypercalcemia and thromboembolic complications, and noted poor survival in advanced stages despite some response to radiation and chemotherapy.

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Abstract

A retrospective analysis of the clinico-pathologic aspects of 22 cases of clear cell ovarian carcinoma with a literature survey is the subject of this report. The rarity of these neoplasms below the age of 40 is reaffirmed. Tumor-related hypercalcemia was observed in two patients and postoperative thromboembolic complications were encountered in three others. Electron microscopic examination revealed abundant cytoplasmic glycogen content in two cases. Ten patients in this group and 26% in reported series had coexistent endometriosis. Association with endometrial carcinoma was observed in two patients and was reported in 14% of the cases. No patient of ours with Stage III or IV disease survived 5 years or longer and only 8% have reportedly survived in collective series. There was suggestive evidence of radiation tumor response in two patients with Stage IIC disease who had received 5,000 rads pelvic radiotherapy. Objective partial responses were also observed with adriamycin-, cytoxan-, and cis-platinum-containing combinations. A management plan is outlined.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Adult Combined Modality Therapy Combined Modality Therapy Female Female Humans Humans Middle Aged Middle Aged Neoplasm Staging Neoplasm Staging Ovarian Neoplasms Ovarian Neoplasms

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (19)

Cited by (6)

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