Thromboembolic complications in patients with clear cell carcinoma of the ovary

Matsuura Y, Yusuke Matsuura, Robertson G, Greg Robertson, Donald E. Marsden, Marsden DE, Soo-Nyung Kim, Soo‐Nyung Kim, Kim SN, Val Gebski, Neville F. Hacker
Gynecologic Oncology · 2006 · vol. 104(2) , pp. 406–410 · doi:10.1016/j.ygyno.2006.08.026 · PMID:17014897 · W2115368232
article OA: closed CC0 ⤵ 11 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-23 ⓘ

This paper investigated thromboembolic complications in patients diagnosed with clear cell carcinoma of the ovary.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

ObjectiveThe purpose of this study was to define the incidence of deep venous thrombosis (DVT) and pulmonary embolism (PE) in patients with clear cell carcinoma (CCC) of the ovary and to investigate the prognostic factors in such patients.MethodsBetween January 1987 and December 2003, 641 women with primary invasive epithelial ovarian cancer underwent treatment at the Royal Hospital for Women in Sydney, Australia. Sixty-six patients (10.3%) with CCC were identified from the data bank, and their data were compared with a matched-control group of 132 patients with non-clear cell epithelial ovarian carcinoma.ResultsA thromboembolic event (DVT or PE) was noted in 27.3% of patients with CCC, compared to 6.8% of patients with other epithelial ovarian cancers. PE was detected in 13.6% and 3.8% of patients, respectively. In patients with CCC, DVT was frequently observed before operation or at the time of recurrence. In a multivariate analysis of patients matched for age and stage, the occurrence of a DVT or the presence of endometriosis was significant predictors of clear cell histology. Within the clear cell group, no particular risk factor for DVT could be identified. Metastases of 50 mm or greater in diameter, ascites of 1000 ml or more, advanced FIGO stage, and the occurrence of DVT were poor prognostic factors for CCC in univariate analysis, but in a multivariate Cox regression analysis, only FIGO stage and occurrence of DVT remained significant.ConclusionThe incidence of venous thromboembolic events was found to be significantly higher in patients with CCC when compared to patients with other epithelial ovarian cancers.

My notes (saved in your browser only)

MeSH descriptors

Adenocarcinoma, Clear Cell Ovarian Neoplasms Pulmonary Embolism Venous Thrombosis Adenocarcinoma, Clear Cell Adult Aged Aged, 80 and over Female Humans Middle Aged Ovarian Neoplasms Pulmonary Embolism Venous Thrombosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (27)

Cited by (11)

Source provenance

europepmc
last seen: 2026-08-03T06:10:56.557307+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:15:12.369988+00:00
License: CC0 · commercial use OK