Tailored hormonal approach in women with premature ovarian insufficiency

F Fruzzetti, Franca Fruzzetti, G. Palla, Marco Gambacciani, M Gambacciani, Tommaso Simoncini
Climacteric : the journal of the International Menopause Society · 2019 · vol. 23(1) , pp. 3–8 · doi:10.1080/13697137.2019.1632284 · PMID:31352836 · W2966446678
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This review proposes an integrated, patient-based hormonal approach for women with premature ovarian insufficiency, addressing fertility, symptoms, and long-term health from puberty to late reproductive age.

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Abstract

Premature ovarian insufficiency (POI) is probably one of the most devastating diagnoses for women of reproductive age. The major implications for fertility, climacteric symptoms, and quality of life, the great impact of long-term consequences such as bone loss and cardiovascular health, and the lack of a coherent and shared clinical approach make the choice for the right hormonal therapy challenging. In this review we propose an integrated and patient-based hormonal approach for women with POI, from puberty to late reproductive age.

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MeSH descriptors

Contraceptives, Oral, Combined Hormone Replacement Therapy Primary Ovarian Insufficiency Adult Cardiovascular Diseases Cardiovascular Diseases Cardiovascular Diseases Child Contraceptives, Oral, Combined Female Hormone Replacement Therapy Humans Patient-Centered Care Patient-Centered Care Primary Ovarian Insufficiency Primary Ovarian Insufficiency Puberty Puberty Quality of Life Young Adult

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License: CC0 · commercial use OK