Ultrasound evaluation of deeply infiltrative endometriosis: technique and interpretation

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This paper describes the technical aspects and imaging interpretation of transvaginal sonography for investigating deeply infiltrative endometriosis.

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This paper describes the technical aspects and interpretation of transvaginal ultrasound for mapping deeply infiltrative endometriosis, including how bowel preparation can reduce artifacts and improve detection of bowel and other lesion sites. It presents transvaginal ultrasound by expert pelvic imagers as a first-line modality capable of providing reliable mapping of affected locations, which is important because routine ultrasound frequently misses deep disease and delayed diagnosis is common. A major caveat noted is that detection of deep lesions can be difficult and may require expert performance and, when applicable, bowel preparation to optimize visualization. This paper is centrally about endometriosis — it focuses specifically on ultrasound technique and interpretation for deeply infiltrative endometriosis.

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Abstract

Endometriosis is a common benign gynecological condition defined as the presence of endometrial tissue located outside the uterus and frequently associated with chronic pelvic pain and infertility. It is a polymorphic disease that can be presented as superficial implants, endometriomas and deep lesions that infiltrate the peritoneal surface associated with fibrosis and inflammatory reaction. Diagnosis of deep endometriosis is difficult and delayed, frequently missed in a routine ultrasound. Transvaginal ultrasound is the first-line imaging modality to investigate endometriosis and when performed by an expert in female pelvic imaging can provide a reliable mapping of the affected sites. Bowel preparation can be used to improve the detection of bowel lesions as well as the other sites affected by eliminating artifacts. Surgery has been the mainstay to treat symptomatic endometriosis and preoperative imaging mapping is crucial for better results and to reduce residual disease. The goals of surgery include radical removal of all lesions and the restoration of normal pelvic anatomy. The author describes technical aspects and imaging interpretation of the transvaginal sonography to investigate deeply infiltrative endometriosis.
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Abstract

Endometriosis is a common benign gynecological condition defined as the presence of endometrial tissue located outside the uterus and frequently associated with chronic pelvic pain and infertility. It is a polymorphic disease that can be presented as superficial implants, endometriomas and deep lesions that infiltrate the peritoneal surface associated with fibrosis and inflammatory reaction. Diagnosis of deep endometriosis is difficult and delayed, frequently missed in a routine ultrasound. Transvaginal ultrasound is the first-line imaging modality to investigate endometriosis and when performed by an expert in female pelvic imaging can provide a reliable mapping of the affected sites. Bowel preparation can be used to improve the detection of bowel lesions as well as the other sites affected by eliminating artifacts. Surgery has been the mainstay to treat symptomatic endometriosis and preoperative imaging mapping is crucial for better results and to reduce residual disease. The goals of surgery include radical removal of all lesions and the restoration of normal pelvic anatomy. The author describes technical aspects and imaging interpretation of the transvaginal sonography to investigate deeply infiltrative endometriosis. Similar content being viewed by others

References

Chamie LP, Blasbalg R, Pereira RM, Warmbrand G, Serafini PC. Findings of pelvic endometriosis at transvaginal US, MR imaging, and laparoscopy. Radiographics. 2011;31(4):E77-100. Giudice LC, Kao LC. Endometriosis. Lancet. 2004;364(9447):1789-99. Maignien C, Santulli P, Gayet V, Lafay-Pillet MC, Korb D, Bourdon M, et al. Prognostic factors for assisted reproductive technology in women with endometriosis-related infertility. Am J Obstet Gynecol. 2017;216(3):280 e1- e9. Lessey BA, Gordts S, Donnez O, Somigliana E, Chapron C, Garcia-Velasco JA, et al. Ovarian endometriosis and infertility: in vitro fertilization (IVF) or surgery as the first approach? Fertil Steril. 2018;110(7):1218-26. Bianchi PH, Pereira RM, Zanatta A, Alegretti JR, Motta EL, Serafini PC. Extensive excision of deep infiltrative endometriosis before in vitro fertilization significantly improves pregnancy rates. J Minim Invasive Gynecol. 2009;16(2):174-80. Abrao MS, Andres MP, Barbosa RN, Bassi MA, Kho RM. Optimizing Perioperative Outcomes with Selective Bowel Resection Following an Algorithm Based on Preoperative Imaging for Bowel Endometriosis. J Minim Invasive Gynecol. 2019. Redwine DB, Wright JT. Laparoscopic treatment of complete obliteration of the cul-de-sac associated with endometriosis: long-term follow-up of en bloc resection. Fertil Steril. 2001;76(2):358-65. Abrao MS, Goncalves MO, Dias JA, Jr., Podgaec S, Chamie LP, Blasbalg R. Comparison between clinical examination, transvaginal sonography and magnetic resonance imaging for the diagnosis of deep endometriosis. Hum Reprod. 2007;22(12):3092-7. Goncalves MO, Podgaec S, Dias JA, Jr., Gonzalez M, Abrao MS. Transvaginal ultrasonography with bowel preparation is able to predict the number of lesions and rectosigmoid layers affected in cases of deep endometriosis, defining surgical strategy. Hum Reprod. 2010;25(3):665-71. Bazot M, Lafont C, Rouzier R, Roseau G, Thomassin-Naggara I, Darai E. Diagnostic accuracy of physical examination, transvaginal sonography, rectal endoscopic sonography, and magnetic resonance imaging to diagnose deep infiltrating endometriosis. Fertil Steril. 2009;92(6):1825-33. Hudelist G, English J, Thomas AE, Tinelli A, Singer CF, Keckstein J. Diagnostic accuracy of transvaginal ultrasound for non-invasive diagnosis of bowel endometriosis: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2011;37(3):257-63. Guerriero S, Ajossa S, Minguez JA, Jurado M, Mais V, Melis GB, et al. Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in uterosacral ligaments, rectovaginal septum, vagina and bladder: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2015;46(5):534-45. Agarwal SK, Chapron C, Giudice LC, Laufer MR, Leyland N, Missmer SA, et al. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol. 2019;220(4):354 e1- e12. Chamie LP, Pereira RM, Zanatta A, Serafini PC. Transvaginal US after bowel preparation for deeply infiltrating endometriosis: protocol, imaging appearances, and laparoscopic correlation. Radiographics. 2010;30(5):1235-49. Pereira RM, Zanatta A, de Mello Bianchi PH, Chamie LP, Goncalves MO, Serafini PC. Transvaginal ultrasound after bowel preparation to assist surgical planning for bowel endometriosis resection. Int J Gynaecol Obstet. 2009;104(2):161. Trippia CH, Zomer MT, Terazaki CR, Martin RL, Ribeiro R, Kondo W. Relevance of Imaging Examinations in the Surgical Planning of Patients with Bowel Endometriosis. Clin Med Insights Reprod Health. 2016;10:1-8. Piketty M, Chopin N, Dousset B, Millischer-Bellaische AE, Roseau G, Leconte M, et al. Preoperative work-up for patients with deeply infiltrating endometriosis: transvaginal ultrasonography must definitely be the first-line imaging examination. Hum Reprod. 2009;24(3):602-7. Goncalves MO, Dias JA, Jr., Podgaec S, Averbach M, Abrao MS. Transvaginal ultrasound for diagnosis of deeply infiltrating endometriosis. Int J Gynaecol Obstet. 2009;104(2):156-60. Guerriero S, Condous G, van den Bosch T, Valentin L, Leone FP, Van Schoubroeck D, et al. Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) group. Ultrasound Obstet Gynecol. 2016;48(3):318-32. Hudelist G, Fritzer N, Staettner S, Tammaa A, Tinelli A, Sparic R, et al. Uterine sliding sign: a simple sonographic predictor for presence of deep infiltrating endometriosis of the rectum. Ultrasound Obstet Gynecol. 2013;41(6):692-5. Leone Roberti Maggiore U, Ferrero S, Candiani M, Somigliana E, Vigano P, Vercellini P. Bladder Endometriosis: A Systematic Review of Pathogenesis, Diagnosis, Treatment, Impact on Fertility, and Risk of Malignant Transformation. Eur Urol. 2017;71(5):790-807. Fettback PB, Pereira RM, Domingues TS, Zacharias KG, Chamie LP, Serafini PC. Uterine rupture before the onset of labor following extensive resection of deeply infiltrating endometriosis with myometrial invasion. Int J Gynaecol Obstet. 2015;129(3):268-70. Chapron C, Pietin-Vialle C, Borghese B, Davy C, Foulot H, Chopin N. Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis. Fertil Steril. 2009;92(2):453-7. Redwine DB. Ovarian endometriosis: a marker for more extensive pelvic and intestinal disease. Fertil Steril. 1999;72(2):310-5. Ghezzi F, Raio L, Cromi A, Duwe DG, Beretta P, Buttarelli M, et al. “Kissing ovaries”: a sonographic sign of moderate to severe endometriosis. Fertil Steril. 2005;83(1):143-7. Kondo W, Branco AW, Trippia CH, Ribeiro R, Zomer MT. Retrocervical deep infiltrating endometriotic lesions larger than thirty millimeters are associated with an increased rate of ureteral involvement. J Minim Invasive Gynecol. 2013;20(1):100-3. Chapron C, Chopin N, Borghese B, Foulot H, Dousset B, Vacher-Lavenu MC, et al. Deeply infiltrating endometriosis: pathogenetic implications of the anatomical distribution. Hum Reprod. 2006;21(7):1839-45. Ribeiro DM, Ribeiro GP, Santos TP, Chamie L, Serafini P, Cretella CM. Multifocal Intestinal Endometriosis and Retrocervical Mantle Shape Endometriosis. The Robotic Treatment - State-of-the-Art. J Minim Invasive Gynecol. 2015;22(6S):S118-S9. Ribeiro DM, Ribeiro GP, Santos TP, Chamie L, Cretella CM, Serafini P. Incidental Appendectomy in the Surgical Treatment of Deep Endometriosis Infiltrating the Bowel: Anatomopathological Findings in a Series of 109 Patients. J Minim Invasive Gynecol. 2015;22(6S):S30-S1. Chamie LP, Ribeiro D, Tiferes DA, Macedo Neto AC, Serafini PC. Atypical Sites of Deeply Infiltrative Endometriosis: Clinical Characteristics and Imaging Findings. Radiographics. 2018;38(1):309-28. Mattos LA, Goncalves MO, Andres MP, Young SW, Feldman M, Abrao MS, et al. Structured Ultrasound and Magnetic Resonance Imaging Reports for Patients with Suspected Endometriosis: Guide for Imagers and Clinicians. J Minim Invasive Gynecol. 2019. Author information Authors and Affiliations Corresponding author Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Electronic supplementary material Below is the link to the electronic supplementary material. Video 1. Assessment of the anterior compartment in the sagittal plane. (AVI 4790 kb) Video 2. Assessment of sliding sign in the anterior compartment (uterovesical region). (AVI 6972 kb) Video 3. Assessment of sliding sign in the right ovary. (MOV 1076 kb) Video 4. Assessment of the left ureteral path in a retrograde manner from the vesicouterine junction up to the adnexal region. (AVI 2413 kb) Video 5. Assessment of the left ureteral peristalsis. (MOV 1457 kb) Video 6. Assessment of the ureteral jet through power Doppler. (AVI 1493 kb) Video 8. Assessment of the posterior compartment by sliding the probe from the anterior into the posterior vaginal fornix. (AVI 7498 kb) Video 9. Assessment of the right uterosacral ligament. (AVI 6882 kb) Video 10. Assessment of the left uterosacral ligament. (AVI 4057 kb) Video 11. Assessment of the vagina. (AVI 6904 kb) Video 12. Assessment of the rectosigmoid colon. (AVI 7524 kb) Video 13. Assessment of DIE affecting the ovarian fossae and its proximity to the left ureteral path. (AVI 4556 kb) Video 14. Assessment of retrocervical DIE. (AVI 6922 kb) Video 15. Assessment of vaginal DIE associated with a right retrocervical lesion. (AVI 7452 kb) Video 16. Assessment of bowel DIE affecting the rectosigmoid colon up to the submucosal layer. (AVI 5253 kb) Rights and permissions About this article Cite this article Chamié, L.P. Ultrasound evaluation of deeply infiltrative endometriosis: technique and interpretation. Abdom Radiol 45, 1648–1658 (2020). https://doi.org/10.1007/s00261-019-02322-7 Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00261-019-02322-7

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Condition tags

endometriosischronic_pelvic_pain

MeSH descriptors

Endometriosis Endometriosis Diagnostic Imaging Female Humans Pelvic Pain Pelvis Ultrasonography

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