Endometrial stem cells: clinical application and pathological roles

Yanping Xu, Xu Y, Zhu H, Huiting Zhu, Zhao D, Dongni Zhao, Tan J, Jichun Tan
International journal of clinical and experimental medicine · 2015 · vol. 8(12) , pp. 22039–44 · PMID:26885178 · PMC4729964 · W2410406719
Review OA: green CC0 ⤵ 9 in-corpus citations
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Endometrial stem cells, particularly MenSCs, hold promise for tissue engineering and regenerative medicine due to their multipotency and low immunogenicity, and may offer insights into endometriosis and endometrial carcinoma.

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Abstract

Adult stem cells occur in human endometrium. Menstrual-blood derived stem cells (MenSCs) are mesenchymal stem cells that can be obtained in a non-invasive manner. Due to their rapid proliferation rate, low immunogenicity, and low tumorigenicity, MenSCs are used extensively in tissue engineering. They can be induced into multiple cell lineages under certain conditions. MenSCs contribute to tissue repair via several different mechanisms, highlighting their great promise in clinical applications. Endometrial stem cells may also be used to shed light on the pathogenesis of endometriosis and endometrial carcinoma. This review will cover recent progress in this field.

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endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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