Adjuvant Therapy of HIFU Ablation for Adenomyosis

In: Adenomyosis · 2021 · pp. 143–148 · doi:10.1007/978-981-33-4095-4_16 · W3133411581
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High-intensity focused ultrasound (HIFU) is effective for adenomyosis but has limitations with recurrence, prompting investigation into adjuvant therapies.

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This chapter reviews high-intensity focused ultrasound (HIFU) as a noninvasive treatment for adenomyosis, focusing on its effectiveness and limitations as adjuvant approaches are considered. It reports that HIFU alone has an effective rate of about 80%–90%, with 10%–20% of patients having symptoms that do not improve significantly, and it cites that symptom recurrence can occur (for example, a retrospective study found a 26% recurrence rate with a median relapse time of 12 months). A key caveat highlighted is that even uterine-uterine preservation strategies can face suboptimal outcomes and recurrence. This paper is centrally about adenomyosis — it discusses adjuvant therapy and the limitations of HIFU ablation outcomes, including recurrence patterns.

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Abstract

At present, many studies have confirmed that HIFU is a safe, effective, and non- invasive method for treating adenomyosis. Still, at the same time, we also realize that this HIFU treatment also has certain limitations. One of them is similar to all other uterine preservation treatment for adenomyosis; patients will face problems of poor results and recurrence. Clinical studies have confirmed that the effective rate of HIFU alone in treating adenomyosis is about 80%–90%, and there are still 10%–20% of patients whose symptoms do not improve significantly. Besides, there are still some patients with symptoms soon recur after treatment. Liu et al. [1] reported that 45 of the 173 patients with adenomyosis after HIFU treatment had symptoms recurred; the recurrence rate was about 26%, and the median time to relapse is 12 months. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

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