The modern non-invasive diagnosis of endometriosis

Felice Petraglia, Silvia Vannuccini, Virginia Manzi, Angela Gallone, Federico Toscano, Francesco La Torre, Gretha Orlandi, Tommaso Capezzuoli, Massimiliano Fambrini
In: Journal of Reproductive Medicine and Embryology · 2024 · vol. 0(0) , pp. 0 · doi:10.21608/jrme.2024.260072.1002 · W4390841073
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This paper explores clinical diagnostic methods, including history, questionnaires, imaging, and biomarkers, as promising non-invasive alternatives to traditional surgical diagnosis for endometriosis.

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Abstract

Endometriosis, a chronic gynecological disease, affects millions of women worldwide, significantly impacting their quality of life. A reported delay, ranging from 4 to 12 years, exists between the onset of symptoms and the formal diagnosis. Characterized by the presence of endometrial-like tissue outside the uterine cavity, this condition often manifests with symptoms such as pelvic pain, dysmenorrhea, and infertility. Traditionally, the gold standard for endometriosis diagnosis has been surgical intervention involving laparoscopy and histological examination. However, the reliance on invasive procedures has led to delayed diagnoses, unnecessary surgeries, and the persistence of symptoms for many patients.In recent years, the value of clinical diagnosis has been shown.The aim is to explore and underscore the significance of clinical diagnostic methods, highlighting their potential for managing endometriosis.Clinical history, questionnaires, imaging modalities, and biomarkers promise to reshape the diagnostic pathway for endometriosis, adopting a more patient-centric, non-invasive diagnostic approach.

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Condition tags

endometriosisdysmenorrheainfertility

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (26)

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last seen: 2026-06-10T17:14:06.276822+00:00
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