Clear cell carcinoma arising from abdominal wall endometriosis: A case report with imaging findings and pathologic correlation

Midori Nakajima, Nakajima M, Kato S, Shinji Kato, Shibata S, Shunsuke Shibata, Kisohara M, Masaya Kisohara, Sagoh H, Haruna Sagoh, Yu Fukaya, Fukaya Y, Itsuki Honda, Honda I, Narumi Watanabe, Watanabe N, Akio Hiwatashi
Radiology case reports · 2026 · vol. 21(8) , pp. 3166–3170 · doi:10.1016/j.radcr.2026.04.042 · PMID:42170565 · W7160695347
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This case report details a clear cell carcinoma arising in abdominal wall endometriosis in a woman with a history of cesarean section, presenting as a painful pubic mass with specific imaging characteristics.

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Abstract

Clear cell carcinoma arising from abdominal wall endometriosis is an exceptionally rare malignancy that typically develops at prior surgical scar sites. We report a case of a woman in her 50s with a history of cesarean section who presented with a gradually enlarging painful pubic mass. Ultrasound detected a lower abdominal wall mass, and contrast-enhanced CT and MRI demonstrated a subcutaneous lesion with mixed cystic and solid components abutting and extending into the rectus abdominis muscle; the solid component showed heterogeneous progressive enhancement and restricted diffusion with a minimum apparent diffusion coefficient of 0.401 × 10-3 mm²/s. Biopsy and subsequent wide excision confirmed clear cell carcinoma arising in abdominal wall endometriosis, and no malignancy was identified in the uterus or adnexa. This case highlights that malignant transformation should be considered when a scar-related abdominal wall mass exhibits a cystic-solid architecture with restricted diffusion, and that ultrasound followed by cross-sectional imaging can facilitate assessment of local invasion and staging.

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Condition tags

endometriosis

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (5)

Source provenance

europepmc
last seen: 2026-10-14T06:08:39.101224+00:00
openalex
last seen: 2026-08-08T06:02:04.998724+00:00
pubmed
last seen: 2026-10-14T06:03:45.875853+00:00
License: CC0 · commercial use OK