Coexistence of mature cystic teratomas and endometriosis

In: Journal of Molecular and Clinical Medicine · 2020 · vol. 3(4) · doi:10.31083/j.jmcm.2020.04.008 · W3114240558
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AI-generated summary by claude@2026-06, 2026-06-07

This review analyzes the epidemiology, clinical presentation, imaging, management, and malignant transformation risk of coexisting mature cystic teratomas and endometriosis, finding diagnosis and treatment more complex than for single diseases.

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AI-generated deep summary by claude@2026-06, 2026-06-07

This paper reviews published English-language reports up to May 2020 on the coexistence of mature cystic ovarian teratomas (MCTs) and endometriosis, including epidemiology, clinical symptoms, imaging findings, management approaches, and risk of malignant transformation; it draws on search results from PubMed and reference tracking rather than new patient data. Across the cited literature, MCTs are often incidentally detected or present with acute complications, while endometriosis commonly causes pelvic pain and dysmenorrhea; in the case-report set, dysmenorrhea and side predominance estimates are summarized, but most individuals were not diagnosed with both conditions before surgery and imaging documentation was limited. A major limitation the paper acknowledges is that available information is sparse and largely based on case reports and a few small studies, constraining firm conclusions about diagnosis and prevalence. Relevance to endometriosis: the paper is centrally about the coexistence of endometriosis with mature cystic ovarian teratomas, compiling how such comorbidity is recognized and characterized in reproductive-age women.

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Abstract

Mature cystic ovarian teratomas are ovarian tumors that are most common in reproductive age women. MCTs are benign germ cell tumors that arise from totipotent germ cells in the ovary. Endometriosis is also a common gynecologic disease affecting reproductive age women. Endometriosis is a progressive and chronic disease associated with inflammation, chronic pelvic pain, and infertility. However, the pathophysiology, symptoms, diagnosis, and management of each disease are well known, but there is little information on the simultaneous occurrence of these two diseases. Therefore, the epidemiology, clinical symptoms, imaging, management, and the risk of malignant transformation of the coexistence of MCTs and endometriosis are discussed herein. PubMed and any reports of individuals with both MCTs and endometriosis were searched for all articles written in the English-language medical literature until May 2020. This review indicates that diagnosis and treatment of the coexistence of MCTs and endometriosis are more complicated when two diseases coexist than when only one disease exists. In conclusion, this comorbid conditions may not be as rare as it was previously thought. To understand and treat this complex condition, more studies are essential.

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Condition tags

endometriosischronic_pelvic_paininfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (76)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
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