Spinal intradural müllerianosis: a case report.

Valeria Barresi, V Barresi, S Cerasoli, E Vitarelli, Enrica Vitarelli, Robert M. Donati, R Donati
Histology and histopathology · 2006 · vol. 21(10) , pp. 1111–4 · doi:10.14670/hh-21.1111 · PMID:16835833 · W2167019442
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This report describes a case of spinal cord müllerianosis in a 42-year-old woman, characterized by a polypoid mass containing endocervical, endometrial, and tubal glands within a smooth muscle nodule.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This case report describes spinal intradural müllerianosis in a 42-year-old woman who had 3 years of catamenial lumbago and sciatica before undergoing L2–L3 laminectomy and excision of a polypoid mass compressing nerve trunks. Histology showed a mixture of endocervical, endometrial, and tubal glands within a smooth muscle nodule, leading to a diagnosis of müllerianosis. The authors note this is an extremely uncommon presentation and emphasize correct identification because patients can benefit from hormonal therapy. Relevance to endometriosis: the case involves müllerian-derived endometrial and endocervical gland tissue presenting with catamenial symptoms, though the paper’s main focus is an isolated spinal müllerianosis case report rather than endometriosis or adenomyosis generally.

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Abstract

Müllerianosis is a term used to indicate lesions composed of an admixture of two or three types of müllerian-derivation glands in heterotopic sites. In this report we describe a case of spinal cord müllerianosis which occurred in a 42-year-old woman. The patient had suffered from catamenial lumbago and sciatica of three years duration before undergoing laminectomy of L2-L3 with excision of a polypoid mass that compressed nerve trunks. At histological examination, the lesion was composed of endocervical, endometrial and tubal glands within a smooth muscle nodule. These features were consistent with a diagnosis of müllerianosis. This is a very uncommon form of presentation of müllerianosis that must be correctly identified since patients can benefit from hormonal therapy.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ependymoma Mixed Tumor, Mullerian Mullerian Ducts Spinal Cord Adult Endometriosis Endometriosis Ependymoma Ependymoma Female Humans Immunohistochemistry Mixed Tumor, Mullerian Mixed Tumor, Mullerian Mullerian Ducts Spinal Cord

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