Phantom endometriosis of the sciatic nerve

L Fedele, Luigi Fedele, S Bianchi, Stefano Bianchi, Ricciarda Raffaelli, R Raffaelli, G. Zanconato, Zanconato G, Giovanni Zanconato, Zanette G, G Zanette, Giampietro Zanette
Fertility and sterility · 1999 · vol. 72(4) , pp. 727–729 · doi:10.1016/s0015-0282(99)00305-2 · PMID:10521118 · W2151185188
article OA: closed CC0 ⤵ 25 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case report details a rare instance of endometriosis affecting the sciatic nerve, presenting diagnostic and surgical considerations for this unusual presentation.

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Abstract

ObjectiveTo assess the efficacy and diagnostic value of GnRH agonist (GnRH-a) therapy in cases of hidden sciatic nerve endometriosis.DesignCase report.SettingAcademic tertiary referral center for endometriosis treatment.Patient(s)Three patients with cyclic, catamenial sciatica associated with pelvic endometriosis who had electromyographic evidence of sciatic nerve damage but negative computed tomography and magnetic resonance imaging findings.Intervention(s)Monthly administration of the GnRH-a leuprolide acetate plus daily transdermal E2 (25 microg).Main outcome measure(s)Relief of pain symptoms and improvement in motor function.Result(s)All three patients had clear decreases in pain and partial amelioration of claudication.Conclusion(s)Endometriosis of the sciatic nerve may be hard to diagnose with the use of current imaging techniques but may be proved by clinical response to GnRH analogue treatment and may be more frequent than previously thought.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Estradiol Leuprolide Peripheral Nervous System Diseases Sciatic Nerve Sciatic Nerve Administration, Cutaneous Adult Drug Administration Schedule Electromyography Endometriosis Endometriosis Estradiol Estradiol Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Leuprolide Leuprolide

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (6)

Cited by (24)

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License: CC0 · commercial use OK