Abnormal (auto)immunity and endometriosis
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⤵ 12 in-corpus citations
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Immunologic abnormalities may precede endometriosis and contribute to infertility and pregnancy loss, suggesting endometriosis is a systemic disease requiring novel therapeutic approaches.
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Abstract
Immunologic abnormalities may precede endometriosis and be involved in its pathophysiology especially as it relates to the occurrence of infertility and pregnancy loss. Many cases of unexplained infertility may represent undiagnosed endometriosis. This is supported by the observation that immunologic profiles in endometriosis and unexplained infertility are very similar. It is argued that endometriosis is a systemic rather than local disease, thus requiring systemic therapy. Currently available medical and surgical techniques are effective in relieving symptomatology associated with endometriosis, although this is often temporary. A new clinical approach is needed that considers systemic presentation and likely immunologic pathophysiology.
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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (12)
- Endometriosis 2020
- Endometriosis 2018
- The impact of the herbal formula Qing Bao Zhu Yu Tang in the treatment of endometriosis 2014
- Endometriosis 2013
- Role of oxidative stress in endometriosis 2006
- Morphological quantitative changes in the number of lymphocytes, macrophages and plasma cells in the uterus and lymph nodes of rats exposed to the systemic administration of BCG 2003
- BCG vaccination to prevent implantation of endometriosis: an experimental study in rats 2001
- Is the endometrium or oocyte/embryo affected in endometriosis? 1999
- Chapter 7 Endometriosis-associated Infertility and New Reproductive Technologies 1999
- Tratamiento endocrinológico de la endometriosis 1997
- Pathogenesis of endometriosis 1997
- Endometrial leukocyte subpopulations in women with endometriosis 1995
Source provenance
- europepmc
- last seen: 2026-10-10T06:11:15.153948+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:59:20.378211+00:00
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