Endometriosis and Pain: Postsurgical Alternative Treatment in Patients Desiring Pregnancy

Errico Zupi, Lucia Lazzeri, Gabriele Centini
In: Journal of Endometriosis and Pelvic Pain Disorders · 2015 · vol. 7(3) , pp. 95–99 · doi:10.5301/je.5000226 · W2173535317
Non-randomised trial OA: closed CC0 ⤵ 4 in-corpus citations
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This pilot study found that a 12-week treatment with a food integrator containing curcumin, quercetin, hyaluronic acid, and chondroitin sulphate significantly reduced painful symptoms in women with endometriosis desiring pregnancy.

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Abstract

Background/aims New pharmacologic agents facilitated and improved the overall management of endometriosis also in case of pregnancy desire. The present study aimed to investigate the efficacy of a food integrator on painful symptoms in endometriotic women looking for pregnancy. Methods This is a pilot study including a group of patients (n = 20) with a previous surgical diagnosis of endometriosis and painful recurring symptoms. A daily dose of two pills of a food integrator containing curcumin, quercetin, hyaluronic acid and chondroitin sulphate (Ialuril Soft gels IBSA, Italy) was self-administered for 12 weeks. Painful symptoms were evaluated by a visual analog scale (VAS) system before and after the end of treatment. Results A significant reduction in the intensity of dysmenorrhea (p<0.001), chronic pelvic pain (p<0.001), and dysuria (p<0.001) compared with the severity of these symptoms before the administration was showed. Conclusions In all patients, the efficacy of Ialuril soft gels was shown after 12 weeks of treatment for dysmenorrhea, chronic pelvic pain and dysuria, thus providing an alternative option for women seeking pregnancy. In the future, further controlled trials will be required, with a larger population and longer follow-up period, to confirm these initial encouraging results.

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Outcome instruments

VAS-pain

Condition tags

endometriosischronic_pelvic_paindysmenorrhea

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (28)

Cited by (4)

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