Can measurement of apparent diffusion coefficient before treatment predict the response to uterine artery embolization for adenomyosis?

Yae Won Park, Yaewon Park, Man Deuk Kim, Dae Chul Jung, Shin Jae Lee, Gyoungmin Kim, Gyoung Min Kim, Sung Il Park, Jong Yun Won, Do Yun Lee
European radiology · 2014 · vol. 25(5) , pp. 1303–1309 · doi:10.1007/s00330-014-3504-3 · PMID:25481638 · W2010959409
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-07 ⓘ

This study investigated whether pre-treatment apparent diffusion coefficient (ADC) measurements can predict the response to uterine artery embolization (UAE) for adenomyosis.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

This prospective study evaluated whether the apparent diffusion coefficient (ADC) measured on pre-treatment diffusion-weighted MRI could predict response to uterine artery embolization (UAE) in 25 patients with symptomatic adenomyosis. After UAE using non-spherical polyvinyl alcohol particles (150–500 μm), follow-up MRI at 3 months defined complete response as ≥90% and incomplete response as <90% of the non-perfusion area with adenomyosis. Patients with complete response had a different mean ADC than those with incomplete response, and an ADC threshold of <1.147 × 10(-3) mm(2)/s yielded sensitivity of 83.3% and specificity of 84.2% for predicting success. The paper’s major limitation is its small sample size (25 patients) and the use of a single follow-up time point (3 months). This paper is centrally about endometriosis/adenomyosis research — it focuses specifically on adenomyosis and uses pre-procedural ADC to predict outcomes after UAE.

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Condition tags

adenomyosis

MeSH descriptors

Adenomyosis Diffusion Magnetic Resonance Imaging Uterine Artery Embolization Adenomyosis Adult Contrast Media Diffusion Magnetic Resonance Imaging Female Humans Image Enhancement Meglumine Myometrium Myometrium Organometallic Compounds Polyvinyl Alcohol Polyvinyl Alcohol Prospective Studies Sensitivity and Specificity Treatment Outcome Uterine Artery Embolization

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (26)

Cited by (12)

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chemicals 1
methylbenzyl alcohol

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