{"paper_id":"2254760f-21b4-414d-ae20-22d28b764067","body_text":"YUHASpace Repository\n0\n1000\nCited 0 times in\nCited 12 times in\nCan measurement of apparent diffusion coefficient before treatment predict the response to uterine artery embolization for adenomyosis?\n- Authors\n- Yaewon Park ; Man Deuk Kim ; Dae Chul Jung ; Shin Jae Lee ; Gyoungmin Kim ; Sung Il Park ; Jong Yun Won ; Do Yun Lee\n- Citation\n- EUROPEAN RADIOLOGY, Vol.25(5) : 1303-1309, 2015\n- Journal Title\n- EUROPEAN RADIOLOGY\n- ISSN\n- 0938-7994\n- Issue Date\n- 2015\n- MeSH\n- Adenomyosis/therapy* ; Adult ; Contrast Media ; Diffusion Magnetic Resonance Imaging/methods* ; Female ; Humans ; Image Enhancement ; Meglumine ; Myometrium/pathology ; Organometallic Compounds ; Polyvinyl Alcohol/therapeutic use ; Prospective Studies ; Sensitivity and Specificity ; Treatment Outcome ; Uterine Artery Embolization/methods*\n- Keywords\n- Uterine arterial embolization ; Adenomyosis ; Magnetic resonance ; Apparent diffusion coefficient ; Prediction of improvement\n- Abstract\n- OBJECTIVES: To determine the usefulness of the apparent diffusion coefficient (ADC) in predicting response to uterine artery embolization (UAE) for symptomatic adenomyosis.\nMETHODS: A prospective study was performed on 25 patients who underwent diffusion-weighted (DW) magnetic resonance imaging (MRI) before UAE between June 2011 and December 2012. All patients underwent 3-month follow-up MRI after UAE using non-spherical polyvinyl alcohol (PVA) particles ranging from 150 to 500 μm. Quantitative measurement of the ADC was performed for each adenomyosis. Complete response and incomplete response were defined as ≥ 90 % or < 90 %, respectively, of the non-perfusion area with adenomyosis at the follow-up MRI. The ADC values were compared between patients who achieved complete or incomplete response which was assessed according to the MRI findings after UAE.\nRESULTS: Nineteen patients showed complete response, and six showed incomplete response. The ADC value ranged from 0.842 to 1.346 × 10(-3) mm(2)/s (mean 1.075 ± 0.117). The mean ADC was 1.043 ± 0.237 in the complete response group and 1.176 ± 0.429 in the incomplete response group (0.012). Using a threshold of <1.147 × 10(-3) mm(2)/s, the sensitivity and specificity of the ADC to predict success after UAE were 83.3 % and 84.2 %.\nCONCLUSION: The ADC of adenomyosis may potentially predict a successful response to UAE for adenomyosis.\nKEY POINTS: • Pre-procedural MRI might help clinicians predict response of UAE in adenomyosis • ADC might help predict UAE outcomes in adenomyosis • MR predictors might be used to counsel patients with symptomatic adenomyosis.\n- Appears in Collections:\n- 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers\n- Yonsei Authors\n-\nKim, Gyoung Min(김경민)\nhttps://orcid.org/0000-0001-6768-4396\nKim, Man Deuk(김만득) https://orcid.org/0000-0002-3575-5847\nPark, Sung Il(박성일)\nPark, Yae Won(박예원) https://orcid.org/0000-0001-8907-5401\nWon, Jong Yun(원종윤) https://orcid.org/0000-0002-8237-5628\nLee, Do Yun(이도연)\nLee, Shin Jae(이신재)\nJung, Dae Chul(정대철) https://orcid.org/0000-0001-5769-5083\nItems in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.","source_license":"CC0","license_restricted":false}