Activity of Peritoneal Macrophages in Endometriosis

T Samejima, Hideaki Masuzaki, H Masuzaki, Tadayuki Ishimaru, T Ishimaru, T Yamabe
Asia-Oceania journal of obstetrics and gynaecology · 1989 · vol. 15(2) , pp. 175–181 · doi:10.1111/j.1447-0756.1989.tb00173.x · PMID:2757577 · W2017860824
article OA: closed CC0 ⤵ 4 in-corpus citations
View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

Peritoneal macrophages from women with endometriosis exhibited significantly higher phagocytic activity compared to controls, suggesting their role in endometriosis-associated infertility.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The mechanism of infertility in women with endometriosis is still largely unclear. It is thought that peritoneal macrophages increase in number in women with endometriosis and that the macrophages phagocytize sperm or the fertilized ovum, leading to infertility. We examined the levels of phagocytosis by peritoneal macrophages in patients with and without endometriosis using a flow cytometric assay. The level of phagocytosis in the control group was significantly lower than in the group with endometriosis. Quantitative results on the level of phagocytosis by peritoneal macrophages suggest that peritoneal macrophages are one of the factors contributing to infertility associated with endometriosis.

My notes (saved in your browser only)

Condition tags

endometriosisinfertility

MeSH descriptors

Endometriosis Macrophages Peritoneal Cavity Endometriosis Female Flow Cytometry Humans Infertility, Female Infertility, Female Macrophages Peritoneal Cavity Phagocytosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (8)

Cited by (4)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:09:10.744835+00:00
unpaywall
last seen: 2026-06-02T02:00:03.124865+00:00
License: CC0 · commercial use OK