Interobserver agreement and accuracy of non-invasive diagnosis of endometriosis by transvaginal sonography

A Tammaa, Tammaa A, Ayman Tammaa, N Fritzer, Fritzer N, P Lozano, Pablo Andrés Ordóñez Lozano, Lozano P, Krell A, A Krell, Salzer H, H. Sälzer, H Salzer, Salama M, M. Salama, Gernot Hudelist, G Hudelist, Hudelist G
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2015 · vol. 46(6) , pp. 737–740 · doi:10.1002/uog.14843 · PMID:25766661 · W2472230668
Diagnostic accuracy OA: bronze CC0 ⤵ 41 in-corpus citations
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Transvaginal sonography demonstrated high interobserver agreement and accuracy for diagnosing deep infiltrating endometriosis and endometriomas compared to laparoscopy.

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Abstract

OBJECTIVES: To evaluate interobserver agreement and accuracy of transvaginal sonography (TVS) in diagnosing deep infiltrating endometriosis (DIE) and endometriomas. METHODS: A total of 67 consecutive patients referred to a pelvic pain clinic and scheduled for laparoscopy were enrolled in the study between January 2013 and January 2014. Patients were independently examined prospectively by two experienced sonographers (Observers A and B) who were blinded to the other's results. For the two observers, Gwet's first-order agreement coefficient (Gwet's AC1) was used to calculate interobserver agreement and diagnostic accuracy, as well as sensitivity, specificity, positive (PPV) and negative (NPV) predictive values using TVS, as compared to laparoscopy, for diagnosing DIE and endometriomas. RESULTS: Among the 67 patients enrolled, 65 were analyzed. For the diagnosis of DIE and endometriomas by TVS, the level of agreement (Gwet's AC1) between Observers A and B and sensitivity/specificity values for the respective Observers were, by site: vagina (Gwet's AC1, 0.933; 62%/94% and 82%/94%), bladder (Gwet's AC1, 1.00; 67%/97% and 67%/97%), uterosacral ligaments (Gwet's AC1, 0.84; 73%/83% and 53%/90%), adnexa (Gwet's AC1, 0.95; 71%/93% and 71%/93%), rectovaginal septum (Gwet's AC1, 0.95; 40%/90% and 33%/87%) and rectosigmoid (Gwet's AC1, 0.98; 93%/96% and 94%/98%) which reflected high interobserver agreement. With the exception of sensitivity of diagnosis of DIE affecting the RVS, similar results were observed when TVS was compared with laparoscopy. CONCLUSIONS: TVS is a highly accurate and reproducible method for non-invasive diagnosis of DIE by well-trained professionals.

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Condition tags

endometriosischronic_pelvic_paindie_deep_infiltrating

MeSH descriptors

Endometriosis Pelvic Pain Vagina Adnexa Uteri Adnexa Uteri Adnexa Uteri Adult Adult Colon, Sigmoid Colon, Sigmoid Colon, Sigmoid Endometriosis Endometriosis Endometriosis Female Female Humans Humans Laparoscopy Laparoscopy

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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Cited by (42)

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