Endometriosis in Reproductive Years: ART and Endometriosis
Endometriosis significantly reduces fertility rates and monthly pregnancy rates, with IVF being an appropriate treatment for advanced cases, reduced ovarian reserve, or compromised tubal function.
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The paper reviews the relationship between endometriosis and infertility in reproductive-age women, synthesizing epidemiologic data and evidence comparing fertility treatments such as IUI and IVF, with attention to ovarian reserve and pelvic abnormalities in advanced disease. It reports that infertility is substantially more common in people with endometriosis (with markedly lower monthly pregnancy rates), that ovarian reserve markers are reduced even when there has been no prior ovarian surgery, and that stage-dependent treatment performance differs, with IVF described as more appropriate for advanced endometriosis with reduced ovarian reserve or compromised tubal function. A key caveat is that it characterizes the relationship as unclear and “poorly understood,” and it states there is no evidence that surgical endometriosis treatment improves ovarian function or enhances IVF success. This paper is centrally about endometriosis — it focuses on how endometriosis affects fertility and how ART approaches relate to infertility in endometriosis.
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