Cancer and Endometriosis: Do We Need to Be Concerned?

Dan C. Martin, D C Martin, Martin DC
Seminars in reproductive endocrinology · 1997 · vol. 15(03) , pp. 319–324 · doi:10.1055/s-2008-1068762 · PMID:9383841 · W2065246681
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⚙ AI-generated summary by claude@2026-06, 2026-06-06 ⓘ

This paper discusses the very low absolute risk of endometrioid ovarian cancer, while highlighting increased risks and management challenges for hormone replacement therapy when endometriosis persists after hysterectomy.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-06 · read from full text ⓘ

This paper discusses concern about cancer risk in the context of endometriosis, focusing on endometrioid carcinoma of the ovary and the overall likelihood of such cancer. It states that the absolute risk of endometrioid ovarian carcinoma is very small, but highlights that leaving endometriosis behind at the time of hysterectomy may increase risk and also create difficulties in managing hormone replacement therapy. It presents these issues as potential considerations related to endometriosis and ovarian malignancy rather than providing new population data. This paper is centrally about endometriosis — it addresses whether endometriosis is a cause for concern regarding endometrioid ovarian carcinoma and management of HRT after hysterectomy.

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Abstract

The absolute risk of endometrioid carcinoma of the ovary is very small. When endometriosis is left behind at the time of hysterectomy, there may be increased risk and difficulties in hormone replacement management.
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Abstract

The absolute risk of endometrioid carcinoma of the ovary is very small. When endometriosis is left behind at the time of hysterectomy, there may be increased risk and difficulties in hormone replacement management.

Keywords

Endometriosis - ovary - cancer - cyst - hormone replacement therapy (HRT) - laparoscope complications

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Condition tags

endometriosis

MeSH descriptors

Carcinoma, Endometrioid Endometriosis Ovarian Neoplasms Antineoplastic Agents, Hormonal Antineoplastic Agents, Hormonal Carcinoma, Endometrioid Endometriosis Estrogen Replacement Therapy Estrogen Replacement Therapy Female Humans Infertility Infertility Ovarian Cysts Ovarian Cysts Ovarian Neoplasms Risk Factors Tamoxifen Tamoxifen

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (14)

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