Medical therapies for chronic menorrhagia

Anita L. Nelson, Stephanie B Teal, Stephanie Teal
Obstetrical & Gynecological Survey · 2007 · vol. 62(4) , pp. 272–281 · doi:10.1097/01.ogx.0000259228.70277.6f · PMID:17371607 · W2037808400
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This review details medical therapies for chronic menorrhagia, including iron, cyclooxygenase inhibitors, antifibrinolytics, and hormonal agents, noting their potential to reduce surgical interventions.

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Abstract

An estimated 10%-30% of menstruating women experience menorrhagia at some time during their reproductive lives. Acute menorrhagia may present as an emergency requiring prompt medical or surgical intervention. Chronic menorrhagia affects a woman's quality of life in her work, family, and social interactions. Medical management is the first line of therapy for chronic menorrhagia. Agents that have been used to treat menorrhagia include iron, cyclooxygenase inhibitors, desmopressin, antifibrinolytics, gonadotropin-releasing hormone agonists, androgens, combined oral contraceptives, and progestins. Progestins can be administered systemically or locally and may be given cyclically or continuously. Increased use of effective medical therapies has the potential to reduce the number of surgical procedures, such as endometrial ablation and hysterectomy.

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MeSH descriptors

Menorrhagia Androgens Androgens Antifibrinolytic Agents Antifibrinolytic Agents Chronic Disease Contraceptives, Oral, Combined Contraceptives, Oral, Combined Cyclooxygenase Inhibitors Cyclooxygenase Inhibitors Female Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone Humans Iron Iron Menorrhagia Progestins Progestins Progestins

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