Treatment of unexplained infertility with danazol

Postgraduate medical journal · 1979 · vol. 55 Suppl 5 , pp. 79–80 · PMID:395525 · W2412250424
RCT OA: closed CC0 ⤵ 5 in-corpus citations
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This randomized trial found that danazol treatment resulted in 3 full-term pregnancies in 21 women with unexplained infertility, compared to none in the 19 placebo recipients.

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Abstract

In order to investigate the possible stimulatory effect of danazol on fertility, a randomized clinical trial was performed on 40 women with unexplained infertility. Twenty-one women received 200 mg danazol daily for 100 days and 19 women received a placebo for the same period. No pregnancies occurred in the placebo group during a 6 month follow-up period. In the danazol group, 5 pregnancies occurred of which 1 were ectopic and 3 went to term.

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Condition tags

infertility

MeSH descriptors

Danazol Infertility, Female Pregnadienes Clinical Trials as Topic Danazol Double-Blind Method Female Humans Infertility, Female Infertility, Female Ovulation Ovulation Pregnadienes Pregnancy

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