Leiomyomas: steroid receptor content. Variation within normal menstrual cycles
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This paper reviews the steroid receptor content of leiomyomas.
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Abstract
In an attempt to clarify further the relationship between ovarian function and uterine leiomyomas, we investigated the cytoplasmic estrogen and progesterone receptor content in these uterine tumors. The study population consisted of 17 women of reproductive age at various stages of ovulatory menstrual cycles. Serum samples were analyzed for estrogen and progesterone content; tissue samples from endometrium, myometrium, and leiomyomas were analyzed for cytoplasmic estrogen and progesterone receptor content. The levels of cytoplasmic estrogen and progesterone receptor in leiomyomas demonstrated the same quantitative and qualitative cyclic changes throughout the menstrual cycle apparently in response to variations in circulating estrogen and progesterone as found in endometrium and myometrium.
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Cited by (12)
- Enlarged uterine corpus volume in women with endometriosis: Assessment using three-dimensional reconstruction of pelvic magnetic resonance images 2016
- Mayer-Rokitansky-Kustner Hauser syndrome complicated by either uterine leiomyoma or ovarian tumor 2010
- Adenomyosis, Leiomyomata, and Pelvic Pain 1998
- Expression of exon 5 deleted estrogen receptor variant messenger RNA in human uterine myometrium and leiomyoma 1998
- Therapeutic effects of leuprorelin microspheres on endometriosis and uterine leiomyomata 1997
- Mifepristone: clinical application in general gynecology 1996
- Immunohistochemical estrogen receptor assessment in hyperplastic, neoplastic, and physiologic endometria 1991
- Studies of the spontaneous motility and the effect of histamine on isolated myometrial strips of the nonpregnant human uterus: the influence of various uterine abnormalities 1990
- Clinicai applications of GnRH analogs 1988
- COMPARISON OF CELLULAR LEVELS OF STEROID RECEPTORS IN UTERINE LEIOMYOMA AND MYOMETRIUM 1985
- Cytochrome P-450 activity in human leiomyoma and normal myometrium 1985
- Obstructive uropathy associated with endometriosis 1985
SciLite annotations
chemicals 7
estrogen
estrogen
progesterone
estrogen
estrogen
estrogen
progesterone
organisms 1
noordeloos 2009062
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:58:32.052686+00:00
- scilite
- last seen: 2026-05-18T04:57:49.680383+00:00
- unpaywall
- last seen: 2026-10-17T06:24:38.187582+00:00
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