Leiomyomas: Steroid receptor content

In: American Journal of Obstetrics and Gynecology · 1982 · vol. 143(1) , pp. 6–11 · doi:10.1016/0002-9378(82)90676-7 · PMID:7081313 · W2406604379
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This paper reviews the steroid receptor content of leiomyomas.

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Abstract

In an attempt to clarify further the relationship between ovarian function and uterine leiomyomas, we investigated the cytoplasmic estrogen and progesterone receptor content in these uterine tumors. The study population consisted of 17 women of reproductive age at various stages of ovulatory menstrual cycles. Serum samples were analyzed for estrogen and progesterone content; tissue samples from endometrium, myometrium, and leiomyomas were analyzed for cytoplasmic estrogen and progesterone receptor content. The levels of cytoplasmic estrogen and progesterone receptor in leiomyomas demonstrated the same quantitative and qualitative cyclic changes throughout the menstrual cycle apparently in response to variations in circulating estrogen and progesterone as found in endometrium and myometrium.

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References (15)

Cited by (12)

SciLite annotations

chemicals 7
estrogen estrogen progesterone estrogen estrogen estrogen progesterone
organisms 1
noordeloos 2009062

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License: CC0 · commercial use OK