Clinical symptoms and histopathological findings in subjects with adenomyosis uteri.

T Cirpan, Cirpan T, Teksin Çırpan, Özgür Yeniel, O Yeniel, Yeniel O, Ulukus M, Murat Ulukuş, M Ulukus, A Ozbal, A Özbal, Ozbal A, Gundem G, Gürsen Gündem, G Gundem, S Ozsener, Ozsener S, Serdar Özşener, Mete Itil I, İsmail Mete, I Mete Itil, O Zekioglu, Zekioglu O, Osman Zekioğlu
Clinical and experimental obstetrics & gynecology · 2008 · vol. 35(1) , pp. 48–53 · PMID:18390081 · W169724032
article OA: closed CC0 ⤵ 11 in-corpus citations
View on OpenAlex View on PubMed
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-10 ⓘ

This study compared clinical symptoms and histopathological findings in 103 adenomyosis patients, finding that deeper myometrial infiltration correlated with increased spread and was significantly associated with dysmenorrhea, anemia, and menometrorrhagia.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

OBJECTIVE: The purpose of this study was to compare the clinical symptoms and histopathological findings in subjects with adenomyosis uteri. METHOD: Infiltration depth and spread of adenomyotic foci together with clinical symptoms and findings were compared in a total of 103 subjects who had undergone hysterectomy and were diagnosed with adenomyosis uteri through histopathological examinations. RESULTS: The spread of adenomyotic foci in myometrial tissues was observed to significantly increase as the depth of myometrial infiltration increased in subjects with adenomyosis (p < 0.05). It was observed that there was significantly higher myometrial infiltration depth in subjects with dysmenorrhea and severe anemia, and diffuse adenomyotic foci in subjects with menometrorrhagia (p < 0.05). CONCLUSION: Increased infiltration depth and spread of adenomyotic foci in myometrial tissues in subjects with adenomyosis uteri were studied. When clinical symptoms and findings in subjects with adenomyosis, such as dysmenorrhea, anemia and menometrorrhagia are compared with these histopathological findings, infiltration depth and spread of adenomyotic foci appear to determine the clinical severity of adenomyosis.

My notes (saved in your browser only)

Condition tags

endometriosisadenomyosisdysmenorrhea

MeSH descriptors

Endometriosis Myometrium Adult Cohort Studies Endometriosis Endometrium Endometrium Female Humans Hysterectomy Middle Aged Myometrium

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (11)

Source provenance

europepmc
last seen: 2026-10-05T06:18:27.067365+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:14:36.758325+00:00
License: CC0 · commercial use OK