Clinical symptoms and histopathological findings in subjects with adenomyosis uteri.
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Abstract
OBJECTIVE: The purpose of this study was to compare the clinical symptoms and histopathological findings in subjects with adenomyosis uteri. METHOD: Infiltration depth and spread of adenomyotic foci together with clinical symptoms and findings were compared in a total of 103 subjects who had undergone hysterectomy and were diagnosed with adenomyosis uteri through histopathological examinations. RESULTS: The spread of adenomyotic foci in myometrial tissues was observed to significantly increase as the depth of myometrial infiltration increased in subjects with adenomyosis (p < 0.05). It was observed that there was significantly higher myometrial infiltration depth in subjects with dysmenorrhea and severe anemia, and diffuse adenomyotic foci in subjects with menometrorrhagia (p < 0.05). CONCLUSION: Increased infiltration depth and spread of adenomyotic foci in myometrial tissues in subjects with adenomyosis uteri were studied. When clinical symptoms and findings in subjects with adenomyosis, such as dysmenorrhea, anemia and menometrorrhagia are compared with these histopathological findings, infiltration depth and spread of adenomyotic foci appear to determine the clinical severity of adenomyosis.
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Cited by (11)
- Perspectives in transvaginal sonography for the diagnosis of adenomyosis 2025
- Evaluating the Efficacy of Radiological Investigations of Adenomyosis with Clinical Symptomatology 2021
- Shi Xiao San ameliorates the development of adenomyosis in an ICR mouse model 2020
- Subtype I (intrinsic) adenomyosis is an independent risk factor for dienogest-related serious unpredictable bleeding in patients with symptomatic adenomyosis 2019
- The impact of adenomyosis on the outcome of IVF–embryo transfer 2017
- Adenomyosis: Pictorial Essay of Two-Dimensional and Three-Dimensional Ultrasonography Findings 2015
- Treatment of adenomyomectomy in women with severe uterine adenomyosis using a novel technique 2014
- UTERINE ADENOMYOSIS IN SOUTHERN THREE-BANDED ARMADILLOS (<i>TOLYPEUTES MATACUS</i>) 2013
- Elevated immunoreactivity to tissue factor and its association with dysmenorrhea severity and the amount of menses in adenomyosis 2010
- Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis 2010
- Increased immunoreactivity to SLIT/ROBO1 and its correlation with severity of dysmenorrhea in adenomyosis 2010
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