Etiology of endometriosis

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AI-generated summary by claude@2026-06, 2026-06-07

Endometriosis is likely a heterogeneous disease with multiple contributing mechanisms, as no single theory fully explains its diverse presentations and pathogenesis.

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Abstract

The etiology and pathogenesis have not been fully elucidated. Many theories have been proposed, but no single theory sufficiently accounts for all aspects of this enigmatic disease, which makes it likely that several mechanisms are involved.2 An alternative explanation is that endometriosis is a heterogeneous rather than a single disease: in other words, peritoneal, deeply infiltrating, ovarian, and extrapelvic endometriosis are manifestations of different disease processes, each with their own etiology.3

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Plasminogen Activators Uterine Neoplasms Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Plasminogen Activators Uterine Neoplasms Uterine Neoplasms

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (1)

Cited by (9)

Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
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