Diagnosis and treatment of endometriosis
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Abstract
Signs and symptoms of endometriosis are non-specific, and an acceptably accurate non-invasive diagnostic test has yet to be reported. Serum markers do not provide adequate diagnostic accuracy. The preferred method for diagnosis of endometriosis is surgical visual inspection of pelvic organs with histologic confirmation. Such diagnosis requires an experienced surgeon because the varied appearance of the disease allows less-obvious lesions to be overlooked. Empiric use of non-steroidal anti-inflammatory drugs or acetaminophen is a reasonable symptomatic treatment, but the effectiveness of these agents has not been well-studied. Oral contraceptive pills, medroxyprogesterone acetate, and intrauterine levonorgestrel are relatively effective for pain relief. Danazol and various gonadotropin-releasing hormone analogues also are effective but may have significant side effects. There is limited evidence that surgical ablation of endometriotic deposits may decrease pain and increase fertility rates in women with endometriosis. Presacral neurectomy is particularly beneficial in women with midline pelvic pain. Hysterectomy and bilateral salpingo-oophorectomy definitively treat pain from endometriosis at 10 years in 90 percent of patients.
South African Family Practice Vol. 49 (3) 2007: pp. 24-29
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Cited by (19)
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- Cervical Cancer or Cervical Endometriosis – Review and Case Report 2023
- The analysis of the prevalence of extragenital pathology in infertile women with external genital endometriosis 2022
- Sensitivity and Specificity of Vascular Endothelial Growth Factor A (VEGF-A) against Endometriosis 2021
- Immunochemical analysis of iron transporters and M2 macrophages in ovarian endometrioma and clear cell adenocarcinoma 2021
- Avaliação das células iNKT em pacientes com endometriose 2019
- Clinical evaluation of laparoscopic surgery combined with triptorelin acetate in patients with endometriosis and infertility 2018
- Feasibility and Safety of Laparoscopic-Assisted Bowel Segmental Resection for Deep Infiltrating Endometriosis: A Retrospective Cohort Study With Description of Technique 2015
- Perioperative Outcomes of Robotic Assisted Laparoscopic Surgery Versus Conventional Laparoscopy Surgery for Advanced-Stage Endometriosis 2014
- Ultrasonographic staging: a new staging system for deep endometriosis 2011
- Models of Endometriosis: Animal Models I – Rodent‐Based Chimeric Models 2011
- Beyond the Boundaries—Endometriosis: Typical and Atypical Locations 2011
- Surgical Management of Infertility Associated With Endometriosis 2010
- Patients' report on how endometriosis affects health, work, and daily life 2009
- EFFECT OF ULTRASOUND THERAPY ON ALLEVIATING PAIN AND ADHESIONS IN ENDOMETRIOSIS 2009
- Gallbladder endometriosis as a cause of occult bleeding 2007
- Prise en charge de l'endométriose: les bonnes pratiques de la cœlioscopie diagnostique 2007
- Endometriosis 1984
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