Eighty consecutive cases of gamete intra-Fallopian transfer*

P C Wong, S C Ng, Margaret Hamilton, M P Hamilton, C Anandakumar, Y C Wong, Yon‐Cheong Wong, S S Ratnam
Human Reproduction · 1988 · vol. 3(2) , pp. 231–233 · doi:10.1093/oxfordjournals.humrep.a136683 · PMID:3281968 · W2343190960
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Gamete intra-Fallopian transfer was performed on 80 patients with unexplained infertility, oligospermia, or endometriosis, resulting in a 31.2% clinical pregnancy rate and a 24% multiple pregnancy rate.

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Abstract

Eighty patients with the main problems of unexplained infertility, oligospermia and endometriosis were treated with gamete intra-Fallopian transfer (GIFT). From 80 treatment cycles, 29 women conceived (36.3%). Of these, four were biochemical pregnancies and therefore the clinical pregnancy rate (25/80) was 31.2%. There were six sets of multiple pregnancies, a multiple pregnancy rate of 24%. Three women (12%) miscarried. The pregnancy rates in the patients with unexplained infertility, oligospermia and endometriosis were 33.3, 16.7 and 38.5%, respectively. The transfer of four oocytes appears to increase the pregnancy rate without increasing the risk of multiple pregnancy. The presence of in-vitro fertilization of excess oocytes after GIFT did not correlate with the final outcome of GIFT.

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Condition tags

endometriosisinfertility

MeSH descriptors

Reproductive Techniques Fallopian Tubes Female Humans Pregnancy

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