A within-patient comparison between superovulation with intra-uterine artificial insemination using husband's washed spermatozoa and gamete intrafallopian transfer in unexplained infertility

C.A. Iffland, Wendy Reid, Nazar N. Amso, A Bernard, Genevieve Buckland, Robert W. Shaw
In: European Journal of Obstetrics & Gynecology and Reproductive Biology · 1991 · vol. 39(3) , pp. 181–186 · doi:10.1016/0028-2243(91)90055-p · PMID:1903346 · W2113279855
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This within-patient study compared superovulation with intrauterine insemination using husband's washed spermatozoa to gamete intrafallopian transfer for treating unexplained infertility.

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Abstract

The purpose of this study was to evaluate the success of gamete intrafallopian transfer (GIFT) and superovulation with intra-uterine artificial insemination (S-IUI) in couples with long-term unexplained infertility. Thirty-nine couples were offered three attempts at each treatment. Sixty-three IUI cycles were completed with a pregnancy rate of 1.5% per cycle. Forty-nine GIFT procedures were carried out with a pregnancy rate of 26.5% per cycle. The cumulative conception rate after three cycles of GIFT was 0.56. GIFT appears to offer a far greater chance of pregnancy than S-IUI in unexplained infertility.

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