Transvaginal ultrasound- and laparoscopy-guided percutaneous microwave ablation for adenomyosis: preliminary results

Jianxin Liu, Jue-Ying Li, Jueying Li, Xiao-Yu Zhao, Xiaoyu Zhao, Qinghua Zhang, Qing-Hua Zhang, Ying Cao, Xiujuan Huang, Xiu-Juan Huang, Xiao-Feng Sun, Sun Xiao, Yuan-Liang Xie, Yuanliang Xie, Shutong Zhang, Shu-Tong Zhang, Yang Shun-shi, Shun-Shi Yang
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2019 · vol. 36(1) , pp. 1232–1237 · doi:10.1080/02656736.2019.1690169 · PMID:31818163 · W2994493689
article OA: gold CC0 ⤵ 8 in-corpus citations
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Transvaginal ultrasound- and laparoscopy-guided percutaneous microwave ablation successfully treated adenomyosis, significantly reducing uterine and lesion volumes, symptom severity, and pain scores.

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Abstract

Purpose: Adenomyosis is a relatively common disease among women of childbearing age. A minimally invasive alternative technique with low risks, faster recovery and decreased side effects is desired. We hypothesized that percutaneous microwave ablation (PMWA) under laparoscopic guidance would substantially reduce the risk of collateral thermal damage to the intestinal tract and relieve the pelvic adhesions. This study aimed to evaluate the feasibility, safety and efficacy of transvaginal ultrasound- and laparoscopy-guided PMWA for the treatment of adenomyosis.Materials and methods: From May 2015 to October 2017, a total of 70 patients with symptomatic adenomyosis who underwent transvaginal ultrasound- and laparoscopy-guided PMWA were included in this study. The technical efficacy and complications of PMWA were assessed. Meanwhile, the uterine volume, lesion volume, symptom severity score (SSS) and visual analog scale (VAS) score before PMWA and at 1, 6 and 12 months after PMWA were recorded.Results: PMWA was successfully performed with transvaginal ultrasound guidance and laparoscope assistance in all patients. No major complication was found after PMWA in any patients. The uterine volume, lesion volume, SSS and VAS were all decreased significantly at follow-up (p < .01).Conclusion: Transvaginal ultrasound- and laparoscopy-guided PMWA, which significantly decreased the uterine volume, lesion volume, SSS and VAS score, is a feasible minimally invasive technique for the treatment of adenomyosis.

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Outcome instruments

VAS-pain

Condition tags

adenomyosis

MeSH descriptors

Ablation Techniques Adenomyosis Adenomyosis Laparoscopy Ultrasonography Vagina Ablation Techniques Adenomyosis Adenomyosis Adult Female Humans Laparoscopy Middle Aged Ultrasonography Vagina

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