[Effect of levonorgestrel-releasing intrauterine system in the treatment of adenomyosis]

Shu-ming He, He SM, Shuming He, Wei MX, Wei Ming-xiu, Ming-xiu Wei, Yan-hua Han, Han YH, Li-hong He, He LH, Lihong He
Zhonghua fu chan ke za zhi · 2005 · vol. 40(8) , pp. 536–8 · PMID:16202292 · W2349662004
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Levonorgestrel-releasing intrauterine system treatment of adenomyosis significantly reduced menstrual blood volume, uterine volume, and dysmenorrhea, while improving hemoglobin in anemic patients.

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Abstract

OBJECTIVE: To assess the clinical efficacy of levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of adenomyosis. METHODS: Forty-two patients with adenomyosis diagnosed by clinical symptoms, MRI, laparoscopy and/or chromatic colour type-B ultrasound were treated with LNG-IUS, and the menstrual blood volume, severity of dysmenorrhea and uterine volume were observed three months later. RESULTS: After 3 month treatment of LNG-IUS, the menstrual blood volume reduced significantly to (27 +/- 11)% of that before treatment. The uterine volume was decreased from (143 +/- 33) cm(3) to (115 +/- 22) cm(3) (P < 0.05). Dysmenorrhea was completely relieved or significantly alleviated. Hemoglobin recovered to (124 +/- 8) g/L (P < 0.05) in 20 patients with anemia. CONCLUSION: LNG-IUS is an effective and safe method in the short-term treatment of adenomyosis.

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Condition tags

endometriosisadenomyosisdysmenorrhea

MeSH descriptors

Endometriosis Levonorgestrel Uterus Adult Adult Endometriosis Endometriosis Female Female Humans Humans Intrauterine Devices Intrauterine Devices Intrauterine Devices, Medicated Intrauterine Devices, Medicated Levonorgestrel Levonorgestrel Levonorgestrel Levonorgestrel Treatment Outcome

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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