[Effect of levonorgestrel-releasing intrauterine system in the treatment of adenomyosis].

Shu-ming He, He SM, Shuming He, Wei MX, Wei Ming-xiu, Ming-xiu Wei, Yan-hua Han, Han YH, Li-hong He, He LH, Lihong He
Zhonghua fu chan ke za zhi · 2005 · vol. 40(8) , pp. 536–8 · PMID:16202292 · W2349662004
article OA: closed CC0 ⤵ 12 in-corpus citations
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Levonorgestrel-releasing intrauterine system treatment of adenomyosis significantly reduced menstrual blood volume, uterine volume, and dysmenorrhea, while improving hemoglobin in anemic patients.

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Abstract

OBJECTIVE: To assess the clinical efficacy of levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of adenomyosis. METHODS: Forty-two patients with adenomyosis diagnosed by clinical symptoms, MRI, laparoscopy and/or chromatic colour type-B ultrasound were treated with LNG-IUS, and the menstrual blood volume, severity of dysmenorrhea and uterine volume were observed three months later. RESULTS: After 3 month treatment of LNG-IUS, the menstrual blood volume reduced significantly to (27 +/- 11)% of that before treatment. The uterine volume was decreased from (143 +/- 33) cm(3) to (115 +/- 22) cm(3) (P < 0.05). Dysmenorrhea was completely relieved or significantly alleviated. Hemoglobin recovered to (124 +/- 8) g/L (P < 0.05) in 20 patients with anemia. CONCLUSION: LNG-IUS is an effective and safe method in the short-term treatment of adenomyosis.

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Condition tags

endometriosisadenomyosisdysmenorrhea

MeSH descriptors

Endometriosis Levonorgestrel Uterus Adult Endometriosis Female Humans Intrauterine Devices Intrauterine Devices, Medicated Levonorgestrel Levonorgestrel Levonorgestrel Treatment Outcome Uterus Uterus

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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