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This review covers the diagnosis and therapeutic management of endometriosis, outlining its definition, prevalence, risk factors, and treatment options.
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This 2023 CMAJ narrative review examines epidemiology, pathophysiology, clinical subtypes, diagnosis, and therapeutic management for endometriosis, synthesizing targeted non-systematic MEDLINE searches and emphasizing clinical practice guidelines and evidence including randomized trials. It summarizes that endometriosis—characterized by estrogen-influenced ectopic pseudo-endometrial tissue—can affect multiple pelvic and extra-pelvic organs, with symptoms such as dysmenorrhea, deep dyspareunia, chronic pelvic pain, and infertility, and it notes that disease extent does not reliably correlate with symptom severity; the review states an explicit limitation that the literature search was targeted and non-systematic. Key findings include that endometriosis may progress, remain stable, or regress over 6–12 months in untreated groups, and that although no curative treatment exists, management includes hormonal suppression, surgery, multidisciplinary pain care, and consideration of central sensitization/nociplastic pain in persistent pain. This paper is centrally about endometriosis — it reviews diagnostic approaches and therapeutic management for the chronic condition.
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Cited by (5)
- Preliminary Materials for a Situated Knowledge of Endometriosis 2026
- Perfil clínico e epidemiológico de pacientes portadoras de endometriose de um serviço ginecológico do Espírito Santo 2025
- Lombalgies persistantes : quels drapeaux du bilan musculosquelettique et de la prise en soin pour suspecter une endométriose ? Propositions de recommandations par une étude Delphi 2025
- Sensibiliser les professionnels de santé à l’endométriose. Conception d’une brochure d’information à destination des masseurs-kinésithérapeutes 2025
- Outpatient diagnosis and drug therapy of endometriosis: A review 2024
Source provenance
- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-06-13T17:19:22.563532+00:00