[Ovarian endometriosis: characteristics of the blood circulatory bed]

L M Mikhaleva, Mikhaleva LM, Л.М. Михалева, N N Vorob'eva, Vorob'eva Nn, M V Samsonova, Samsonova Mv
Arkhiv patologii · 2006 · vol. 68(4) , pp. 20–2 · PMID:16986490 · W2413658214
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Glandular cystic ovarian endometriosis exhibits a denser blood supply and higher epithelial proliferation, correlating with CA-125 levels, which indicates morphofunctional activity and disease progression potential.

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Abstract

Glandular cystic ovarian endometriosis (OE) is characterized by a more intensive blood supply than cystic OE. This type of OE is characterized by a high proliferative glandular epithelial activity detected by an immunohistochemical study using antibodies to PCNA and CA-125. Moreover, a positive correlation is found between the serum concentration of CA-125 and the expression of this antigen in the epitheliocytes of an endometrioid cyst in both glandular-cystic and cystic OE. Thus, the findings permit the determination of the morphofunctional activity of a type of OE and its aptness to the progression of the disease and to the development of recurrences.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Ovary Adolescent Adolescent Adult Adult CA-125 Antigen CA-125 Antigen CA-125 Antigen Disease Progression Disease Progression Endometriosis Endometriosis Endometriosis Female Female Humans Humans Microcirculation

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

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