Intestinal and pelvic endometriosis presenting as a tumor and associated with tamoxifen therapy: Report of a case
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A case of extensive tumor-like pelvic and intestinal endometriosis developed in a postmenopausal breast cancer patient after 2 years of tamoxifen therapy.
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Abstract
BACKGROUND: Tamoxifen has been used in the adjuvant treatment of breast cancer because of its antiestrogenic effects. However, recent reports have shown it to have estrogenic effects as well. The purpose of this report is to describe a potential association between tamoxifen therapy and endometriosis. CASE: A 50-year-old postmenopausal woman who had received 2 years of adjuvant tamoxifen therapy for breast carcinoma developed extensive tumor-like endometriosis necessitating extensive pelvic and intestinal surgery. CONCLUSION: This case report highlights the need for obstetricians and gynecologists to be familiar with the actions of tamoxifen and its potential complications.
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Cited by (13)
- Horizons in Endometriosis: Proceedings of the Montreux Reproductive Summit, 14-15 July 2023 2024
- Endometriosis in Menopausal Women—A New Age Is Coming? Literature Review 2024
- Bilateral ovarian endometriomas after laparoscopic hysterectomy following adjuvant tamoxifen therapy for breast cancer: A case report 2022
- Endometriosis in Menopause—Renewed Attention on a Controversial Disease 2020
- Polypoid endometriosis mimicking invasive cancer in an obese, postmenopausal tamoxifen user 2017
- Endometriosis after Menopause 2015
- Peritoneal endometriosis in the broad ligament presenting as a large tumor 2002
- Tamoxifen treatment and gynecologic side effects: a review 2001
- Benign, Borderline, and Malignant Endometrioid Neoplasia Arising in Endometriosis in Association with Tamoxifen Therapy 2000
- Tamoxifen‐associated postmenopausal adenomyosis exhibits stromal fibrosis, glandular dilatation and epithelial metaplasias 2000
- Ovarian Histopathology in Breast Cancer Patients Receiving Tamoxifen 1999
- Re: Renal and Diaphragmatic Endometriosis De Novo Associated with Hormone Replacement Therapy 1995
- Endometriosis and tamoxifen therapy 1994
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