Potential impact of vitamin D on women’s reproductive health

A. N. Vodolazkaya, S. V. Orlova, Е. А. Никитина, E. V. Prokopenko, Yu. A. Pigareva, Н. В. Балашова
In: Medical alphabet · 2023 · pp. 23–28 · doi:10.33667/2078-5631-2023-8-23-28 · W4380610293
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This review examines clinical studies on vitamin D's role in modulating fertility indicators, highlighting the need for further randomized trials.

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This paper is a narrative review examining the potential impact of vitamin D on women’s reproductive health, synthesizing experimental evidence and summarizing clinical studies related to fertility and reproductive-system functioning. Across the reviewed literature, vitamin D is described as potentially modulating metabolic and hormonal parameters associated with female fertility, and the paper highlights mechanistic and clinical findings from diverse study designs. The authors explicitly conclude that, despite accumulated data, further randomized clinical trials are needed to clarify vitamin D’s effects on fertility outcomes. Relevance to endometriosis: the manuscript’s reference list includes epidemiology-focused articles on endometriosis (e.g., Viganò et al., Parazzini et al.), though the review’s main focus is vitamin D and women’s reproductive health rather than endometriosis specifically.

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Abstract

In recent years, the role of vitamin D in women’s reproductive health has been widely studied. Accumulated experimental evidence suggest that vitamin D may play a modulating role in the metabolic and hormonal indicators of women’s fertility. This review reflects numerous of clinical studies on the potential impact of vitamin D on the female reproductive system. Analysis of data indicates the need for further randomized clinical trials of vitamin D.
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Потенциальное влияние витамина D на репродуктивное здоровье женщины https://doi.org/10.33667/2078-5631-2023-8-23-28 Аннотация Роль витамин D в женском репродуктивном здоровье широко изучается последние годы. Накоплены экспериментальные данные, свидетельствующие о том, что витамин D может играть модулирующую роль в метаболических и гормональных показателях фертильности женщин. Данный обзор отображает многочисленные клинические исследования потенциального влияния витамина D на репродуктивную систему женщины. Однако анализ данных свидетельствует о необходимости проведения дальнейших рандомизированных клинических испытаний витамина D в отношении фертильности. Об авторах А. Н. ВодолазкаяРоссия Водолазкая Ангелина Николаевна, врач-диетолог Москва С. В. Орлова Россия Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии Москва Е. А. Никитина Россия Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии Москва Е. В. Прокопенко Россия Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, ведущий менеджер проектов медицинского департамента Москва Ю. А. Пигарева Россия Пигарева Юлия Анатольевна, к. м. н., зав. отделением клинической диетологии Москва Н. В. Балашова Россия Балашова Наталья Валерьевна, к. б. н., ассистент доцент кафедры диетологии и клинической нутрициологии Список литературы 1. Filippov O. S. Causes and factors of infertility development among the population of Siberia. Epidemiology and infectious diseases. 2002 (3): 47. 2. Ustinova T. A., Artymuk N. V., Vlasova V. V., Pyzhov A. Ya. Infertility in the Kemerovo region. Mother and child in Kuzbass. 2010;1(40):37–9. 3. Frolova N. I., Belokrinitskaya T. E., Anokhova L. I. The prevalence and characteristics of infertility in women of young fertile age, living in the Trans-Baikal Territory. Acta Biomed. Sci. 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Рецензия Для цитирования: Водолазкая А.Н., Орлова С.В., Никитина Е.А., Прокопенко Е.В., Пигарева Ю.А., Балашова Н.В. Потенциальное влияние витамина D на репродуктивное здоровье женщины. Медицинский алфавит. 2023;(8):23-28. https://doi.org/10.33667/2078-5631-2023-8-23-28 For citation: Vodolazkaya A.N., Orlova S.V., Nikitina E.A., Prokopenko E.V., Pigareva Yu.A., Balashova N.V. Potential impact of vitamin D on women’s reproductive health. Medical alphabet. 2023;(8):23-28. (In Russ.) https://doi.org/10.33667/2078-5631-2023-8-23-28 JATS XML

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