Severe recurrent endometriomas in a young woman with congenital von Willebrand disease

Francesca Rizzello, Rizzello F, Eleonora Ralli, Ralli E, Romanelli C, Chiara Romanelli, Maria Elisabetta Coccia
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2019 · vol. 35(12) , pp. 1040–1042 · doi:10.1080/09513590.2019.1641481 · PMID:31311362 · W2958494429
Case report OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-16 ⓘ

This case describes a young woman with von Willebrand disease who developed severe recurrent ovarian endometriomas, suggesting vWD may be a risk factor for aggressive endometriosis.

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Abstract

The pathophysiology of severe endometriosis in young women remains unknown. Menorrhagia, or heavy and prolonged menstrual bleeding, is the most common symptom experienced by women with von Willebrand disease (vWD) and represents a possible risk factor for developing endometriosis. A 17-year-old woman affected by vWD presented with severe dysmenorrhea and heavy menstrual bleeding. After being diagnosed with multiple ovarian endometriomas, the patient underwent repeated surgeries due to suspicious appearance of recurrent pelvic masses. vWD may be a risk factor for developing severe endometriosis, and patients with endometriosis should be screened for vWD and other bleeding disorders. Ovarian endometriomas in such patients might present a more severe progression and unique ultrasound findings, mimicking malignancies.

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Condition tags

endometriosisdysmenorrhea

MeSH descriptors

Endometriosis Menorrhagia Ovarian Diseases von Willebrand Disease, Type 3 Adolescent Adolescent Contraceptives, Oral, Combined Contraceptives, Oral, Combined Contraceptives, Oral, Combined Endometriosis Endometriosis Endometriosis Endometriosis Female Female Gynecologic Surgical Procedures Gynecologic Surgical Procedures Humans Humans Menorrhagia

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (24)

Cited by (6)

Source provenance

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