Additional file 1 of The effects of coagulation factors on the risk of endometriosis: a Mendelian randomization study

Li, Yan, Liu, Hongyan, Ye, Shuting, Zhang, Bumei, Li, Xiaopei, Yuan, Jiapei, Du, Yongrui, Wang, Jianmei, Yang Yang
2023 · doi:10.6084/m9.figshare.23167889.v1 · W6977464315
dataset OA: green CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This Mendelian randomization study selected instrumental variables for coagulation factors and analyzed their causal effects on endometriosis using UK Biobank and FinnGen data, with additional analyses for sub-phenotypes and genetic correlations.

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Abstract

Additional file 1: Table S1. Selected instrumental variables for coagulation factors in this study. Table S2. Summary statistics of the causal estimates of coagulation factors on endometriosis in UK Biobank. Table S3. The results of leave-one-out analyses for endometriosis in UK Biobank. Table S4. Summary statistics of the causal estimates of coagulation factors on endometriosis in FinnGen. Table S5. The results of leave-one-out analyses for endometriosis in FinnGen. Table S6. Summary statistics of the causal estimates of coagulation factors on endometriosis in the meta-analysis. Table S7. The results of leave-one-out analyses for endometriosis in the meta-analysis. Table S8. Summary statistics of the causal estimates of vWF and ADAMTS13 on different sub-phenotypes of endometrioses. Table S9. Genetic correlations between endometriosis of uterus (adenomyosis) and other sub-phenotypes.

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Condition tags

endometriosisadenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (57)

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