Malignant transformation of superficial peritoneal endometriosis lesion

Eva Marchand, Delphine Hequet, Delphine Héquet, Anne Thoury, A. Thoury, Emmanuel Barranger
BMJ case reports · 2013 · vol. 2013 , pp. bcr2012007730 · doi:10.1136/bcr-2012-007730 · PMID:23978494 · W2171422217
article OA: bronze CC0 ⤵ 9 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-11 ⓘ

This report describes a rare case of malignant transformation in a superficial peritoneal endometriosis lesion that was surgically removed and showed no recurrence after 18 months.

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Abstract

A 63-year-old woman with no medical history underwent an abdominal surgery with hysterectomy and bilateral salpingo-oophorectomy for a 10 cm peritoneal cyst with increased cancer antigene-125. A large suspicious tumour of the Douglas space, with contact to the uterus and the rectal wall was described. The rest of the exploration was normal, specially the rest of the peritoneum. Histopathology revealed a malignant transformation of a superficial peritoneal endometriosis. Secondary surgery was thus completed by laparoscopy with bilateral pelvic and para-aortic lymph node dissections, omentectomy and multiple peritoneal biopsies. All staging samples were free of cancer; therefore no complementary therapy was administered. After 18 months of follow-up, consisting of clinical examination and pelvis magnetic resonance imaging every 6 months, we did not observe any recurrence. Malignant transformation of superficial peritoneal endometriosis is a rare disease and surgical management seems to be the main treatment.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Carcinoma, Endometrioid Cell Transformation, Neoplastic Douglas' Pouch Endometriosis Peritoneal Neoplasms Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Douglas' Pouch Endometriosis Female Humans Hysterectomy Middle Aged Ovariectomy Peritoneal Diseases Peritoneal Diseases Peritoneal Neoplasms Peritoneal Neoplasms Salpingectomy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (19)

Cited by (9)

Source provenance

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