JBRA assisted reproduction

OBJECTIVE: The aim of this study was to investigate whether there were differences in the number of good-quality blastocysts after 6 days of treatment with r-hFSH followed by late follicular phase treatment with r-hFSH:r-hLH in a 2:1 fixed …

Endometriosis is a chronic, inflammatory, and multifactorial disease characterized by the presence of endometrial tissue outside the uterine cavity, often associated with debilitating symptoms. It affects approximately 10% of women of repro…

Chemotherapy remains a cornerstone of cancer treatment, effectively targeting rapidly dividing cancer cells, yet its systemic effects often extend to healthy reproductive cells, resulting in temporary or permanent infertility. This review e…

OBJECTIVE: To compare the effectiveness of microfluidic sperm sorting (MC) and traditional density gradient centrifugation (DGC) in reducing sperm DNA fragmentation index (DFI) and evaluate their impact on clinical outcomes in IVF cycles. …

OBJECTIVE: Thin endometrium is an increasingly recognized challenge in infertility treatment. This study aimed to compare endometrial gene expression between women with thin and normal endometrial thickness, and also to identify ovarian sti…

OBJECTIVE: Since cumulus cells (CCs) play an undeniable role in oocyte maturation by producing and transferring important molecules to the oocyte, examining these cells can provide a broad view of the factors affecting oocyte competence. Th…

OBJECTIVE: To evaluate whether endometrial thickness (EMT) is associated with pregnancy rates in frozen embryo transfer (FET) cycles. METHODS: This retrospective study analyzed medical records of patients who underwent FET between January …

OBJECTIVE: Endometriosis is a chronic estrogen-dependent inflammatory disease that impairs fertility and quality of life. Dienogest, the current standard therapy, provides symptom relief but does not correct immune imbalance or prevent recu…

OBJECTIVE: The etiopathogenesis of endometriosis-related infertility remains under investigation, including in women with endometriomas. Oocyte quality is believed to play an important role in the impairment of natural fertility in these pa…

Endometriosis is a chronic inflammatory disease that affects around 10% of women of reproductive age and is frequently associated with infertility. Despite its high prevalence in assisted reproductive technology (ART) cycles, the exact mech…

This systematic review and meta-analysis of randomized controlled trials (RCTs) evaluated whether the use of hyaluronic acid (HA)-enriched medium for embryo transfer (ET) improves live birth rates in in-vitro fertilization (IVF) cycles. A c…

OBJECTIVE: To assess whether the diagnosis and antibiotic treatment of chronic endometritis improve reproductive outcomes in patients with recurrent pregnancy loss or recurrent implantation failure. METHODS: This retrospective study includ…

OBJECTIVE: To assess the prevalence, authorship, and reliability of educational fertility-related information shared on Brazilian Instagram, measured by the DISCERN instrument. METHODS: This cross-sectional study analyzed public fertility-…

OBJECTIVE: To detect the presence of seminal HPV and examine its association with semen quality in men from infertile and fertile couples. METHODS: This single-center case-control study involved 50 men from infertile couples and 10 proven-…

OBJECTIVE: This study aims to evaluate and characterize Assisted Reproductive Technology (ART) cycles, as well as the associated obstetric and neonatal outcomes, in pregnancies resulting from gamete donation at the Public Gamete Bank of the…

In vitro fertilization (IVF) has transformed infertility treatment, providing options for individuals struggling to conceive naturally, with significant success rates, particularly in women under 35. However, IVF pregnancies are associated …

OBJECTIVE: To compare clinical, obstetric, and neonatal outcomes between natural and artificial endometrial preparation protocols for frozen embryo transfer (FET) in cycles involving single euploid blastocyst transfer. METHODS: This retros…

OBJECTIVE: This study investigates the effects of Piperine (PIP) on doxorubicin (DOX)-induced changes in mouse ovarian follicles, stromal cells, collagen fibers, and mRNA expression of nuclear factor erythroid 2-related factor (NRF2), super…

OBJECTIVE: Endometriosis is a gynecological disorder marked by the formation of endometrial tissue (gland and stroma) outside the uterine cavity. Macrophages, erythrocytes, and apoptotic endometrial tissue transplant into the peritoneal cav…

OBJECTIVE: Morphologic assessment of an embryo is a valuable indicator for determining embryo health; however, it does not provide information on the chromosomal status of an embryo. Therefore, this study aimed to investigate the levels of …

OBJECTIVE: To evaluate the association between antithyroid antibodies detectability and positivity and ovarian reserve. Additionally, we aimed to evaluate the correlation between TSH levels and parameters of ovarian reserve [anti-Mullerian …

In assisted reproductive technologies, a major challenge is the relatively low overall success rate, mainly due to the absence of reliable markers for assessing oocyte and embryo quality. This study focuses on identifying new biomarkers in …

Considering the significant exposure to the synthetic compound bisphenol A (BPA), present in a wide range of materials in our daily lives, this article discusses a possible correlation between this substance and human fertility through a bi…

OBJECTIVE: Infertility is a major global health issue, with assisted reproductive technologies (ART) commonly employed as a solution. Although numerous factors related to couple characteristics and ART cycles are implicated in pregnancy out…